evidence/gaps
Cochrane · systematic review · CD002783

Thrombolytic strategies versus standard anticoagulation for acute deep vein thrombosis of the lower limb

Broderick, C, Watson, L, Armon, MP · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Vascular2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 4 · 100%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Treatment with any thrombolysis strategy for acute deep vein thrombosis

Population: patients diagnosed with acute DVT
4 questions
OutcomeEffectEvidenceStatus / GRADE
Complete clot lysis (intermediate, 6 months to under 5 years after treatment)
RR 2.42 [1.42, 4.12]7 studies · 654 participantsModerate
Bleeding (early, up to 1 month after treatment)
RR 2.45 [1.58, 3.78]19 studies · 1943 participantsModerate
Post‐thrombotic syndrome (intermediate, 6 months to under 5 years after treatment)
RR 0.78 [0.66, 0.93]6 studies · 1393 participantsModerate
Post‐thrombotic syndrome (late, 5 years
RR 0.56 [0.43, 0.73]2 studies · 211 participantsModerate