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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Primary outcome: topical local anaesthetics vs placebo or no treatment

Parental satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Hand mallet (osteotomes) vs Electric mallet

Complication at augmented site · Patients undergoing one-stage crestal maxillary sinus lift without bone grafts (baseline residual bone height about 6.5 mm)

Hand mallet (osteotomes) showed no clear difference in complications at augmented site compared with electric mallet; GRADE not reported.

1 finding from 1 review

Intraligamental injection local anaesthetic vs no treatment

Physiological parameters (cardiac/respiratory events; type and volume of GA drug) · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Frankel's function regulator-4 (FR-4) with lip-seal training vs no treatment

Reduction of snoring · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…

The review found no eligible studies for this question.

1 finding from 1 review

Autogenous bone graft (two-stage lateral sinus lift) vs Bone substitute (anorganic bovine bone / Bio-Oss)

Implant failure · Patients with an atrophic posterior maxilla requiring maxillary sinus augmentation

Autogenous bone graft (two-stage lateral sinus lift) showed no clear difference in implant failure compared with bone substitute (anorganic bovine bone / Bio-Oss); GRADE not reported.

1 finding from 1 review

Repelling-magnet splints vs Bite-blocks

Anterior open bite correction · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…
1 finding from 1 review
  • Orthodontic and orthopaedic treatment for anterior open bite in children 2014 · Cochrane All outcomes
    About 4 months (treatment interrupted early)
    Could not be analysed statistically. After 4 months the open bite was observed to close in the magnet group, but in four out of these ten patients transverse problems (unilateral crossbite) were observed, which led to…
    1 study
    GRADE not reported

NobelActive external connection implants vs NobelActive internal connection implants

Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

NobelActive external connection implants showed no clear difference in implant failure compared with nobelActive internal connection implants; GRADE not reported.

1 finding from 1 review

Powered toothbrush, rotation oscillation action vs Manual toothbrush

Gingivitis · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)

Powered toothbrush, rotation oscillation action led to lower gingivitis score (1 to 3 months) compared with manual toothbrush; GRADE not reported.

2 findings from 1 review

Bone graft with platelet-rich plasma (PRP) vs Bone graft without PRP

Implant failure · Patients with insufficient bone below the maxillary sinus requiring dental implants
1 finding from 1 review

NobelActive internal connection implants vs Nobel Speedy Groovy external connection implants

Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

NobelActive internal connection implants led to lower marginal bone level change compared with nobel Speedy Groovy external connection implants; GRADE not reported.

1 finding from 1 review

Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone)

Augmentation procedure failure · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height)

Sinus lift with bone graft (granular Bio-Oss) showed no clear difference in augmentation procedure failure compared with sinus lift without bone graft (Inion resorbable rigid barrier…; GRADE not reported.

1 finding from 1 review

Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)

Number of visits · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to adults up to 48-54 years)

Surgical anchorage (mini-screw or mid-palatal implant) led to higher number of visits compared with conventional anchorage (headgear, transpalatal/palatal arch, etc.); GRADE not reported.

1 finding from 1 review

Powered toothbrush (any mode of action) vs Manual toothbrush

Plaque · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)

Powered toothbrush (any mode of action) probably leads to lower plaque score (1 to 3 months) compared with manual toothbrush (moderate certainty).

2 findings from 1 review

Thalidomide (systemic; 100 mg or 300 mg daily) vs placebo

Number of (minor aphthous) oral ulcers · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
  • Interventions for managing oral ulcers in Behçet's disease 2014 · Cochrane All outcomes
    Males only
    Hamuryudan 1998 (thalidomide 100 mg or 300 mg daily vs placebo, 101 male patients; high risk of reporting bias): a significant effect on mean numbers of minor oral ulcers was reported from week 4 in both thalidomide…
    1 study · 101 participants
    GRADE not reported

Rotary instruments to open the lateral sinus window vs Piezosurgery to open the lateral sinus window

Complication at augmented site · Patients undergoing lateral-window maxillary sinus lift

Rotary instruments to open the lateral sinus window showed no clear difference in complications at augmented site compared with piezosurgery to open the lateral sinus window; GRADE not reported.

1 finding from 1 review

Powered toothbrush, ultrasonic action vs Manual toothbrush

Plaque · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)
2 findings from 1 review