Cochrane · intervention · CD005515

Orthodontic and orthopaedic treatment for anterior open bite in children

Lentini‐Oliveira, DA, Carvalho, FR, Rodrigues, CG, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

Oral HealthOrthodontics3 versionsAMSTAR 2: not assessed
Full textEvery question was extracted from the full review (methods and results), not only its Summary of Findings table.
Questions
19
current version
GRADE rated
0
No studies
8
Included studies
3
as reported
No studies 8 · 42.1%Ungraded 11 · 57.9%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Review question

ElementPlanned (methods)Found (results)
PopulationChildren and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of contact or vertical overlap between upper and lower front teeth); who have stopped any sucking habits 1 year or more before treatment; do not have a class III skeletal relationship, cleft lip or palate, or other syndrome associated with craniofacial anomaliesThree included studies (120 participants): Kiliaridis 1990 (Sweden, n=20); Erbay 1995 (Turkey, n=40); Almeida 2005 (Brazil, n=60). Ages ranged from 7 years 5 months to 16 years 1 month. Two studies required skeletal anterior open bite; anterior open bite of at least 1 mm was an inclusion criterion in two studies
InterventionOrthodontic or orthopaedic (non-surgical) treatment used to correct anterior open bite: Orthopaedic functional appliances (e.g. Simoes Network 2 (SN2), Simoes Network 3 (SN3), Frankel's function regulator-4 (FR-4)); Fixed orthodontic appliances (e.g. multiloop edgewise archwire (MEAW), Mcloughlin, Bennett, Trevisi); Removable orthodontic appliances (e.g. tongue crib appliances, fixed intraoral habit appliances, removable habit-breaker)Frankel's function regulator-4 with lip-seal training (n=20); Repelling-magnet splints (n=10); Removable appliance with palatal crib associated with high-pull chincup (n=30)
ComparisonNo intervention; Another techniqueNo treatment (n=50); Bite-blocks (n=10)
OutcomesPrimary: Correction of the anterior open bite (contacts/overlap between upper and lower central incisors; plaster models, cephalometric data, clinical assessment); Secondary: Stability of correction (1 year); Expansion of the upper and lower jaws; Incisor position and inclination; Alteration of hyperdivergent growth pattern; Mandibular ramus growth; Reduction of snoring; Signs and symptoms of respiratory disease (mouth breathing, nasal airway resistance); Signs and symptoms of atypical swallowing and speech disturbances; Reduction or treatment of OSAS or UARS; Economic evaluation (costs); Drop-outs; Side effects/tolerability; Patient satisfactionAnterior open bite correction (n=3); Incisor position and inclination (n=2); Alteration of hyperdivergent growth pattern (n=2); Mandibular ramus growth (n=2); Expansion of the upper and lower jaw (n=1); Side effects/adverse effects (unilateral crossbite) (n=1)
Study designsRandomised controlled trials (RCTs); quasi-randomised trials eligible (subjected to sensitivity analysis)Randomised controlled trials (n=3)
TimingNot specified (stability of correction assessed 1 year after treatment)Treatment duration: FR-4 with lip-seal training 2 years; repelling-magnet splints vs bite-blocks 6 months (interrupted at about 4 months); palatal crib with high-pull chincup 12 months

Search date: 2014-02. Databases: The Cochrane Oral Health Group's Trials Register; The Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE via OVID; EMBASE via OVID; LILACS via BIREME Virtual Health Library; Brazilian Bibliography of Odontology (BBO) via BIREME Virtual Health Library; SciELO; ClinicalTrials.gov

Questions and results

Show all 3 versions

Frankel's function regulator-4 (FR-4) with lip-seal training vs No treatment

Population: Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or contact of the upper and lower incisors); sucking habits stopped 1 year or more before treatment; excluding class III skeletal relationship, cleft lip or palate, or other craniofacial syndrome
12 questions
OutcomeEffectEvidenceStatus / GRADE
Failure to correct the anterior open bite (open bite not closed)
End of treatment (about 2 years)
RR 0.02 [0.00, 0.38]1 study · 40 participantsUngraded
Signs and symptoms of respiratory disease (mouth breathing, nasal airway resistance)
Outcome proposed in the review but not found in any included study. The review states: 'The other outcomes proposed in this review were not found: stability of anterior open bite correction; reduction of snoring; signs…0 studiesNo studies
Economic evaluation (costs)
Outcome proposed in the review but not found in any included study. The review states: 'The other outcomes proposed in this review were not found: stability of anterior open bite correction; reduction of snoring; signs…0 studiesNo studies
Reduction or treatment of obstructive sleep apnoea syndrome (OSAS) or upper airway resistance syndrome (UARS)
Outcome proposed in the review but not found in any included study. The review states: 'The other outcomes proposed in this review were not found: stability of anterior open bite correction; reduction of snoring; signs…0 studiesNo studies
Mandibular ramus growth
End of treatment (about 2 years)
The author reported no difference between groups in mandibular ramus growth (linear measure Ar-Go). No pooled estimate.1 studyUngraded
Patient satisfaction
Outcome proposed in the review but not found in any included study. The review states: 'The other outcomes proposed in this review were not found: stability of anterior open bite correction; reduction of snoring; signs…0 studiesNo studies
Stability of anterior open bite correction (1 year after treatment)
Outcome proposed in the review but not found in any included study. The review states: 'The other outcomes proposed in this review were not found: stability of anterior open bite correction; reduction of snoring; signs…0 studiesNo studies
Position of the incisors (upper incisor inclination)
End of treatment (about 2 years)
The angulation of the upper incisors with the palatal plane (1/ANSPNS) decreased on average 0.3 (SD 4.6) degrees in the control group, whereas in the treated group the mean retrusion was 4 (SD 4.6) degrees, P < 0.01.…1 studyUngraded
Alteration of hyperdivergent growth pattern
End of treatment (about 2 years)
Multiple cephalometric measures reported (Erbay 1995). Treated group: total anterior facial height (N-Me) +3.9 (SD 1.8) mm, upper anterior facial height (N-ANS) +3.3 (SD 1.2) mm; controls showed significantly greater…1 studyUngraded
Signs and symptoms of atypical swallowing and speech production disturbances
Outcome proposed in the review but not found in any included study. The review states: 'The other outcomes proposed in this review were not found: stability of anterior open bite correction; reduction of snoring; signs…0 studiesNo studies
Reduction of snoring
Outcome proposed in the review but not found in any included study. The review states: 'The other outcomes proposed in this review were not found: stability of anterior open bite correction; reduction of snoring; signs…0 studiesNo studies
Side effects / tolerability
Outcome proposed in the review but not found in any included study. The review states: 'The other outcomes proposed in this review were not found: stability of anterior open bite correction; reduction of snoring; signs…0 studiesNo studies

Repelling-magnet splints vs Bite-blocks

Population: Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or contact of the upper and lower incisors); sucking habits stopped 1 year or more before treatment; excluding class III skeletal relationship, cleft lip or palate, or other craniofacial syndrome
2 questions
OutcomeEffectEvidenceStatus / GRADE
Side effects / adverse effects (unilateral crossbite; transverse problems)
About 4 months (treatment interrupted early)
"After 4 months the open bite was observed to close in the magnet group, but in four out of these ten patients, transverse problems were observed (unilateral crossbite) which led to the interruption of the treatment…1 study · 10 participantsUngraded
Anterior open bite correction
About 4 months (treatment interrupted early)
Could not be analysed statistically. After 4 months the open bite was observed to close in the magnet group, but in four out of these ten patients transverse problems (unilateral crossbite) were observed, which led to…1 studyUngraded

Removable appliance with palatal crib associated with high-pull chincup vs No treatment

Population: Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or contact of the upper and lower incisors); sucking habits stopped 1 year or more before treatment; excluding class III skeletal relationship, cleft lip or palate, or other craniofacial syndrome
5 questions
OutcomeEffectEvidenceStatus / GRADE
Mandibular ramus growth
End of treatment (12 months)
Cephalometric data (SNA, Co-A, SNB, Ar-Go, Ar.GoMe, Co-Gn, ANB) were reported to be not significantly different between groups; effects were dento-alveolar rather than skeletal. No pooled estimate (Almeida 2005).1 studyUngraded
Expansion of the upper and lower jaw
End of treatment (12 months)
Listed among the outcome measures evaluated by Almeida 2005. No separate width/expansion estimate is reported in the text; the review concluded the interventions produced no significant change in the skeletal maxillary…1 studyUngraded
Alteration of hyperdivergent growth pattern
End of treatment (12 months)
The angles (SN.GoGN, SN.PP, NS.Gn) and linear measures (AFA, AFP, AFAI) did not demonstrate significant alterations between groups; interventions did not produce significant changes in the skeletal maxillary or…1 studyUngraded
Position of the incisors (upper incisor inclination)
End of treatment (12 months)
The author reported that data (1.NA, 1-NA, 1-PP, 1.NB, 1-NB, 1-GoMe) showed a statistically significant difference. There was palatal inclination of the upper incisors in the intervention group that contributed to…1 studyUngraded
Failure to correct the anterior open bite (open bite not closed)
End of treatment (12 months)
RR 0.23 [0.11, 0.48]1 study · 60 participantsUngraded