Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Absorbable vs non‐absorbable sutures

DASH hand function score at 3 months Major outcome group 1 (hand function) (scores between 0 and 100, where 0 represents no impairment in hand function and 100 represents maximum impairment in hand function)

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings TIVA vs inhalational maintenance of anaesthesia

Postoperative delirium (One study used DRS, three studies used CAM and in one study diagnostic tool was not reported) Time points were up to 4 days postoperatively

It is very uncertain whether summary of findings TIVA changes postoperative delirium (One study used DRS, three studies used CAM… compared with inhalational maintenance of anaesthesia (very low certainty).

1 finding from 1 review

Summary of findings TIVA vs inhalational maintenance of anaesthesia

Postoperative cognitive dysfunction (9 studies used MMSE, and 2 of these studies used additional diagnostic tools; 1 study used Trail Making Test and additional diagnostic tools; 3 studies did not report diagnostic tools) Time points were up to 30...

Summary of findings TIVA may leads to lower postoperative cognitive dysfunction (9 studies used MMSE, and 2 of… compared with inhalational maintenance of anaesthesia (low certainty).

1 finding from 1 review

Biological graft vs native tissue repair

Awareness of prolapse (subjective failure) (16‐24 months) · women with posterior vaginal wall prolapse

Biological graft showed no clear difference in awareness of prolapse (subjective failure) (16‐24 months) compared with native tissue repair (moderate certainty).

1 finding from 1 review

Biological graft vs native tissue repair

Recurrent posterior vaginal wall prolapse (objective failure) (12‐25 months) · women with posterior vaginal wall prolapse

Biological graft showed no clear difference in recurrent posterior vaginal wall prolapse (objective failure) (16‐24… compared with native tissue repair (low certainty).

1 finding from 1 review

Biological graft vs native tissue repair

Postoperative obstructed defecation (16‐24 months) · women with posterior vaginal wall prolapse

Biological graft showed no clear difference in postoperative obstructed defecation (16‐24 months) compared with native tissue repair (moderate certainty).

1 finding from 1 review