Cochrane · systematic review · CD012271
Daikenchuto for reducing postoperative ileus in patients undergoing elective abdominal surgery
Hoshino Nobuaki, Takada Toshihiko, Hida Koya, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
ColorectalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 4 · 57.1%Low 2 · 28.6%Moderate 1 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Daikenchuto compared to control for reducing postoperative ileus
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time from completion of operation to first flatus (hours) Daikenchuto vs control | no estimate extracted | 2 studies · 83 participants | Very low Downgraded: risk of bias |
Time from completion of operation to first bowel movement (hours) Daikenchuto vs control | no estimate extracted | 4 studies · 500 participants | Very low Downgraded: risk of bias |
Time from completion of operation to resumption of regular solid food intake (hours) Daikenchuto vs control | no estimate extracted | 2 studies · 258 participants | Very low Downgraded: risk of bias |
Any drug‐related adverse events (CTCAE grade ≥ 2) Daikenchuto vs control | RD 0 | 5 studies · 568 participants | Low Downgraded: risk of bias |
Patient satisfaction on day of discharge (Gastrointestinal Symptom Rating Scale (GSRS)) Daikenchuto vs control | no estimate extracted | 1 study · 81 participants | Very low Downgraded: risk of bias |
Incidence ratio of any re‐interventions before leaving hospital Daikenchuto vs control | RR 0.99 [0.06, 15.62] | 1 study · 207 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Length of postoperative hospital stay (days) Daikenchuto vs control | no estimate extracted | 3 studies · 292 participants | Low Downgraded: risk of bias |