Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,747 questions · 3,943 findings · 594 reviews

No studies found 784 · 19.9%GRADE not reported 530 · 13.4%Very low 1,040 · 26.4%Low 981 · 24.9%Moderate 444 · 11.3%High 164 · 4.2%

Intervention not reported

Asthma exacerbation as defined by hospital admission or treatment with a course of oral corticosteroids · participants with exercise‐induced asthma

The review found no eligible studies for this question.

1 finding from 1 review

PDHA program with robust prevention vs PDHA program or PDHA program with intensive staffing

Tooth decay-free children · Alaska children aged 5 to 18 years

The robust prevention PDHA model was projected to yield more than 50% tooth decay-free children versus 8% with other PDHA models, without a GRADE rating.

1 finding from 1 review

Primary dental health aide (PDHA) service-delivery models (PDHA program; PDHA + intensive staffing; PDHA + robust prevention) vs Baseline pre-intervention service-delivery scenario

Projected Significant Caries (SiC) index · Alaska Native children (below age 18)

A simulation projected a 50% drop in the Significant Caries index for children (12.3 to 6.1) under the PDHA model (certainty not graded).

2 findings from 1 review

Primary dental health aide (PDHA) service-delivery models (PDHA program; PDHA + intensive staffing; PDHA + robust prevention) vs Baseline pre-intervention service-delivery scenario

Projected proportion of caries-free children (5-18 years) · Alaska Native children (below age 18)

A simulation projected 0% of children aged 5-18 would be caries-free under the baseline scenario (certainty not graded).

3 findings from 1 review

DHAT-delivered dental care vs Dentist-delivered dental care

Technical performance / deficient restorations (DHATs vs dentists) · Alaska Native dental patients (children aged 6-17 and adults) and their caregivers

DHATs had a lower amalgam restoration deficiency rate than dentists (12% vs 22%; certainty not graded).

3 findings from 1 review

DHAT-delivered dental care vs Not applicable (single-group prevalence)

Clinical care quality · Alaska dental health aide therapists

Four newly trained DHATs met stated clinical care standards in a qualitative evaluation, without a GRADE rating.

1 finding from 1 review

Primary dental health aide (PDHA) service-delivery models (PDHA program; PDHA + intensive staffing; PDHA + robust prevention) vs Baseline pre-intervention service-delivery scenario

Projected receipt of school-based prevention services · Alaska Native children (below age 18)

A simulation projected that over 90% of children would receive school-based prevention services under the PDHA model, up from 53% (certainty not graded).

1 finding from 1 review

DHAT-delivered dental care vs Dentist-delivered dental care

Caregiver satisfaction · Caregivers of Alaska Native children aged 6 to 17 years

More than 90% of caregivers reported being usually or always satisfied with DHAT care, without a GRADE rating.

1 finding from 1 review

DHAT-delivered dental care vs Dentist-delivered dental care

Composite restoration deficiency · Alaska dental health aide therapists

Composite restoration deficiency was 15% for DHATs versus 12% for dentists, without a GRADE rating.

1 finding from 1 review

DHAT-delivered dental care vs Dentist-delivered dental care

Consistency of diagnosis and postoperative complications · Alaska dental health aide therapists

No significant difference was reported between DHATs and dentists in diagnosis consistency or postoperative complications, without a GRADE rating.

1 finding from 1 review

DHAT-delivered dental care vs Dentist-delivered dental care

Stainless steel crown preparation and placement deficiency · Alaska dental health aide therapists

No stainless steel crown preparation deficiencies were reported; placement deficiency was 3% for DHATs versus 9% for dentists, without a GRADE rating.

1 finding from 1 review

Intervention not reported

Achieved recovery according to predetermined criteria (no longer meeting criteria for depression on K‐SADS or meeting a priori criteria for response on a depression checklist, assessed between 4 and 10 weeks of onset of treatment) · children and adolescents with depression

The intervention showed no clear difference in achieved recovery according to predetermined criteria (no longer… (low certainty).

1 finding from 1 review

Intervention not reported

Change in depression checklist scores (BID, CDI, CDRS, DACL or HAM‐D from baseline to between 2 and 10 weeks) · children and adolescents with depression
1 finding from 1 review