Development of endocarditis (in those with definite indication for prophylaxis) · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure
It is very uncertain whether antibiotic prophylaxis before dental procedure changes development of endocarditis (in those with definite indication for… compared with no antibiotic prophylaxis or placebo (very low certainty).
1 finding from 1 review
Presence of dry socket · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
Systemic antibiotic prophylaxis (any regimen; topical therapy… may leads to lower dry socket compared with placebo (low certainty).
1 finding from 1 review
Infectious complications · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
Systemic antibiotic prophylaxis (any regimen; topical therapy… may leads to lower postsurgical infectious complications compared with placebo (low certainty).
1 finding from 1 review
Swelling (7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes swelling (7th day) compared with placebo (very low certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes pain (continuous, VAS 0-10 cm, 7th day) compared with placebo (very low certainty).
1 finding from 1 review
Pain (dichotomous, present/absent on 6th-7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes presence of pain (dichotomous, yes/no on 6th-7th day) compared with placebo (very low certainty).
1 finding from 1 review
Intervention not reported
Complete clot lysis (intermediate, 6 months to under 5 years after treatment) · patients diagnosed with acute DVT
The intervention probably leads to higher complete clot lysis (intermediate, 6 months to under 5 years after… (moderate certainty).
1 finding from 1 review
Intervention not reported
Bleeding (early, up to 1 month after treatment) · patients diagnosed with acute DVT
The intervention probably leads to higher bleeding (early, up to 1 month after treatment) (moderate certainty).
1 finding from 1 review
Intervention not reported
Post‐thrombotic syndrome (intermediate, 6 months to under 5 years after treatment) · patients diagnosed with acute DVT
The intervention probably leads to lower post‐thrombotic syndrome (intermediate, 6 months to under 5 years… (moderate certainty).
1 finding from 1 review
Intervention not reported
Post‐thrombotic syndrome (late, 5 years · patients diagnosed with acute DVT
The intervention probably leads to lower post‐thrombotic syndrome (late, 5 years (moderate certainty).
1 finding from 1 review
Chronic pelvic pain at 12 months Â
1 finding from 1 review
Dysmenorrhoea at 12 months Â
1 finding from 1 review
Improvement of the most troublesome symptom at 12 months Â
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life at 12 months Â
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient satisfaction at 12 monthsÂ
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events Â
1 finding from 1 review
Â
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Overall pain at 12 months Â
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Primary outcomes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Impacts on management or information systems (if not a targeted measure of performance)
1 finding from 1 review
no estimate extracted
Studies not reported
Low