Findings

What do systematic reviews say?

462 questions · 474 findings · 56 reviews · Eyes and Vision

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No studies found 147 · 31%GRADE not reported 15 · 3.2%Very low 89 · 18.8%Low 157 · 33.1%Moderate 52 · 11%High 14 · 3%

Botulinum toxin vs surgery

Quality of life (validated questionnaire) · adults and children with strabismus

The review found no eligible studies for this question.

1 finding from 1 review

Botulinum toxin for the treatment of strabismus 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Botulinum toxin vs surgery

Non‐serious adverse events at 6 or 12 months · adults and children with strabismus

1 finding from 1 review

Botulinum toxin for the treatment of strabismus 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 212 participants
Low

Combined steroid and antibiotic therapy vs antibiotics alone

Outcomes* · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive steroid therapy versus antibiotics alone for acute endophthalmitis after intraocular procedure 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Combined steroid and antibiotic therapy vs antibiotics alone

Complete resolution of endophthalmitis at 3 months' · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)

It is very uncertain whether combined steroid and antibiotic therapy changes complete resolution of endophthalmitis at 3 months' compared with antibiotics alone (very low certainty).

1 finding from 1 review

Adjunctive steroid therapy versus antibiotics alone for acute endophthalmitis after intraocular procedure 2022 · Cochrane Headline outcomes only
RR 1.08 [0.8, 1.45]
1 study · 32 participants
Very low

Combined steroid and antibiotic therapy vs antibiotics alone

Visual acuity · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)

Combined steroid and antibiotic therapy may leads to higher visual acuity 6/6 to 6/18 at 3 months' compared with antibiotics alone (low certainty).

2 findings from 1 review

Adjunctive steroid therapy versus antibiotics alone for acute endophthalmitis after intraocular procedure 2022 · Cochrane Headline outcomes only
RR 1.95 [1.05, 3.6]
2 studies · 60 participants
Low
Adjunctive steroid therapy versus antibiotics alone for acute endophthalmitis after intraocular procedure 2022 · Cochrane Headline outcomes only
RR 1.12 [0.92, 1.37]
2 studies · 195 participants
Low

Combined steroid and antibiotic therapy vs antibiotics alone

Improvement in visual acuity at 3 months' · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive steroid therapy versus antibiotics alone for acute endophthalmitis after intraocular procedure 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Combined steroid and antibiotic therapy vs antibiotics alone

Intraocular pressure ( · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)

1 finding from 1 review

Adjunctive steroid therapy versus antibiotics alone for acute endophthalmitis after intraocular procedure 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 167 participants
Low

Combined steroid and antibiotic therapy vs antibiotics alone

Adverse events at 3 to 12 months' · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)

Combined steroid and antibiotic therapy showed no clear difference in adverse events at 3 to 12 months' compared with antibiotics alone (low certainty).

1 finding from 1 review

Adjunctive steroid therapy versus antibiotics alone for acute endophthalmitis after intraocular procedure 2022 · Cochrane Headline outcomes only
RR 1.41 [0.53, 3.74]
3 studies · 227 participants
Low

Combined steroid and antibiotic therapy vs antibiotics alone

Costs · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive steroid therapy versus antibiotics alone for acute endophthalmitis after intraocular procedure 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Aqueous shunts with vs without mitomycin C

Mean intraocular pressure · adults with glaucoma requiring aqueous shunt surgery

1 finding from 1 review

Aqueous shunts with mitomycin C versus aqueous shunts alone for glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 78 participants
Low

Aqueous shunts with vs without mitomycin C

Difference in mean IOP from baseline at < 6 months · adults with glaucoma requiring aqueous shunt surgery

The review found no eligible studies for this question.

1 finding from 1 review

Aqueous shunts with mitomycin C versus aqueous shunts alone for glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Aqueous shunts with vs without mitomycin C

Visual acuity · adults with glaucoma requiring aqueous shunt surgery

The review found no eligible studies for this question.

1 finding from 1 review

Aqueous shunts with mitomycin C versus aqueous shunts alone for glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Aqueous shunts with vs without mitomycin C

Proportion of participants with stable best‐corrected visual acuity · adults with glaucoma requiring aqueous shunt surgery

The review found no eligible studies for this question.

1 finding from 1 review

Aqueous shunts with mitomycin C versus aqueous shunts alone for glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Aqueous shunts with vs without mitomycin C

Decrease in visual acuity · adults with glaucoma requiring aqueous shunt surgery

The review found no eligible studies for this question.

1 finding from 1 review

Aqueous shunts with mitomycin C versus aqueous shunts alone for glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Aqueous shunts with vs without mitomycin C

Proportion of participants with a postoperative hypertensive phase · adults with glaucoma requiring aqueous shunt surgery

The review found no eligible studies for this question.

1 finding from 1 review

Aqueous shunts with mitomycin C versus aqueous shunts alone for glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Aqueous shunts with vs without mitomycin C

Proportion of participants with an adverse event · adults with glaucoma requiring aqueous shunt surgery

1 finding from 1 review

Aqueous shunts with mitomycin C versus aqueous shunts alone for glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 85 participants
Low

Toric intraocular lens (IOL) vs limbal relaxing incisions (LRIs)

Postoperative residual refractive astigmatism of less than 0.50 D · people with astigmatism who are having cataract surgery (phacoemulsification)

Toric intraocular lens (IOL) probably leads to higher postoperative residual refractive astigmatism of less than 0.50 D compared with limbal relaxing incisions (LRIs) (moderate certainty).

1 finding from 1 review

Toric intraocular lens versus limbal relaxing incisions for corneal astigmatism after phacoemulsification 2019 · Cochrane Headline outcomes only
RR 1.4 [1.1, 1.78]
5 studies · 262 participants
Moderate

Toric intraocular lens (IOL) vs limbal relaxing incisions (LRIs)

Postoperative residual refractive astigmatism in dioptres · people with astigmatism who are having cataract surgery (phacoemulsification)

1 finding from 1 review

Toric intraocular lens versus limbal relaxing incisions for corneal astigmatism after phacoemulsification 2019 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 620 participants
Low

Toric intraocular lens (IOL) vs limbal relaxing incisions (LRIs)

Visual acuity · people with astigmatism who are having cataract surgery (phacoemulsification)

1 finding from 1 review

Toric intraocular lens versus limbal relaxing incisions for corneal astigmatism after phacoemulsification 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 474 participants
Moderate

Toric intraocular lens (IOL) vs limbal relaxing incisions (LRIs)

Spectacle independence for distance as reported by the participant · people with astigmatism who are having cataract surgery (phacoemulsification)

Toric intraocular lens (IOL) may leads to higher spectacle independence for distance as reported by the participant compared with limbal relaxing incisions (LRIs) (low certainty).

1 finding from 1 review

Toric intraocular lens versus limbal relaxing incisions for corneal astigmatism after phacoemulsification 2019 · Cochrane Headline outcomes only
RR 1.56 [1.14, 2.15]
2 studies · 100 participants
Low