Skin damage № of participants: 1587 (4 RCTs) · patients with a central venous catheter
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Pain № of participants: 193 (2 RCTs) · patients with a central venous catheter
Longer intervals (5‐15 days) (intervention) showed no clear difference in pain № of participants: 193 (2 RCTs) compared with shorter intervals (2‐5 days) (control) between dressing changes (low certainty).
1 finding from 1 review
RR 0.8 [0.46, 1.38]
Studies not reported
Low
Adverse effects · People with avulsed and replanted permanent (front) teeth
1 finding from 1 review
Day 2012 used a formal methodology to identify and report adverse effects, with none identified.
1 study · 22 participants
GRADE not reported
Aesthetics (discolouration) at 12 months (patient level) · People with avulsed and replanted permanent (front) teeth
It is very uncertain whether ledermix root canal medicament (day 0 to 10) changes aesthetics (discolouration) at 12 months (patient level) compared with ultracal root canal medicament (day 7 to 10) (very low certainty).
1 finding from 1 review
Tooth survival · People with avulsed and replanted permanent (front) teeth
1 finding from 1 review
Tooth survival at 12 months: Not estimable (due to no events in either arm); 27 teeth in 22 patients (1 RCT). At 12 months, no teeth were lost. 1 tooth was lost at 16 months in the Ultracal group.
1 study · 22 participants
Very low
Periodontal healing at 12 months · People with avulsed and replanted permanent (front) teeth
It is very uncertain whether ledermix root canal medicament (day 0 to 10) changes periodontal healing at 12 months (tooth level) compared with ultracal root canal medicament (day 7 to 10) (very low certainty).
1 finding from 1 review
Complete cure, at least 3 months after the end of treatment · People with American cutaneous and mucocutaneous leishmaniasis
Oral miltefosine (1.2 to 3.3 mg/kg/d 28 days) showed no clear difference in complete cure, at least 3 months after the end of treatment compared with meglumine antimoniate (20 mg/kg 20 days) (low certainty).
1 finding from 1 review
Adverse effects (number of participants who had the event) · People with American cutaneous and mucocutaneous leishmaniasis
Oral miltefosine (1.2 to 3.3 mg/kg/d 28 days) probably leads to higher adverse effects (number of participants who had the event) compared with meglumine antimoniate (20 mg/kg 20 days) (moderate certainty).
1 finding from 1 review
Recurrence ‐ not measured · People with American cutaneous and mucocutaneous leishmaniasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Global state: clinically important change in global state · patients with schizophrenia
1 finding from 1 review
Mental state: clinically important response in mental state BPRS score >30% change · patients with schizophrenia
Clozapine: low dose (150 mg/day to 300 mg/day) showed no clear difference in mental state: clinically important response in mental state BPRS… compared with standard dose (301 mg/day to 600 mg/day) (low certainty).
1 finding from 1 review
Functioning: clinically important change in general functioning, as defined by individual studies · patients with schizophrenia
1 finding from 1 review
Adverse effect: clinically important adverse effect (weight ‐ BMI) · patients with schizophrenia
1 finding from 1 review
Service use: time to hospitalisation · patients with schizophrenia
1 finding from 1 review
Quality of life: clinically important change in quality of life · patients with schizophrenia
1 finding from 1 review
Incidence of asymptomatic bacteriuria · postoperative kidney transplant patients
It is very uncertain whether urinary catheter removal < 5 days postoperatively changes incidence of asymptomatic bacteriuria compared with urinary catheter removal ≥ 5 days postoperatively (very low certainty).
1 finding from 1 review
Incidence of symptomatic UTI · postoperative kidney transplant patients
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Incidence of major urological complications · postoperative kidney transplant patients
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Death from any cause · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
It is very uncertain whether long‐stored ('older') PRBC (≥ 21 days of storage) changes death from any cause compared with short‐stored (fresh) PRBC (< 21 days of storage) (very low certainty).
1 finding from 1 review
Transfusion‐related acute lung injury ‐ not measured · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found