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Evidence found and GRADE certainty

379 questions · 472 findings · 38 reviews

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No studies found 115 · 24.4%GRADE not reported 157 · 33.3%Very low 89 · 18.9%Low 63 · 13.3%Moderate 36 · 7.6%High 12 · 2.5%

Chlorhexidine dressing following alcohol cleansing vs polyurethane dressing following aqueous povidone‐iodine cleansing

Adverse effects: contact dermatitis · newborn infants with central venous catheters

Chlorhexidine dressing following alcohol cleansing probably leads to higher adverse effects: contact dermatitis compared with polyurethane dressing following aqueous povidone‐iodine cleansing (moderate certainty).

1 finding from 1 review

Silver‐alginate dressing vs control

CRBSI ‐ Unit of analysis: infants Clinical and microbiological methods · newborn infants with central venous catheters

Silver‐alginate dressing showed no clear difference in CRBSI ‐ Unit of analysis: infants Clinical and microbiological methods compared with control (moderate certainty).

1 finding from 1 review

Silver‐alginate dressing vs control

CRBSI ‐ Unit of analysis: catheters Clinial and microbiological methods · newborn infants with central venous catheters

Silver‐alginate dressing showed no clear difference in CRBSI ‐ Unit of analysis: catheters Clinial and microbiological… compared with control (moderate certainty).

1 finding from 1 review

Combined oral and intravenous vs oral or intravenous alone

Wound infection · colorectal surgery

Combined oral and intravenous leads to lower surgical wound infection: oral + iv versus iv alone compared with oral or intravenous alone (high certainty).

2 findings from 1 review

Azithromycin vs erythromycin

Bacteriological failure · Adults and children with cholera diarrhoea

Azithromycin showed no clear difference in bacteriological failure compared with erythromycin (low certainty).

1 finding from 1 review

Tetracycline vs doxycycline

Bacteriological failure · Adults and children with cholera diarrhoea

Tetracycline probably leads to lower bacteriological failure compared with doxycycline (moderate certainty).

1 finding from 1 review

Tetracycline vs quinolones

Bacteriological failure · Adults and children with cholera diarrhoea

Tetracycline showed no clear difference in bacteriological failure compared with quinolones (low certainty).

1 finding from 1 review

Doxycycline vs quinolones

Bacteriological failure · Adults and children with cholera diarrhoea

Doxycycline may leads to higher bacteriological failure compared with quinolones (low certainty).

1 finding from 1 review