Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Summary of findings table ‐ Subcutaneous biologics (dupilumab) vs placebo

Short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of · adults with alopecia areata

Summary of findings table ‐ Subcutaneous biologics (dupilumab) showed no clear difference in short‐term hair regrowth ≥ 75% compared with placebo (low certainty).

1 finding from 1 review

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Locoregional recurrence · women with breast cancer and one to three positive lymph nodes

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) may leads to lower local and regional recurrence (LRR) compared with no PMRT (low certainty).

1 finding from 1 review

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Overall survival (OS) · women with breast cancer and one to three positive lymph nodes

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) probably leads to lower overall survival (OS) compared with no PMRT (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Selective prevention interventions vs control group

Adverse events at study endpoint · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Selective prevention interventions vs control group

Psychological functioning and impairment at study endpoint (higher score = higher disability) · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Selective prevention interventions vs control group

Depressive symptoms · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Selective prevention interventions vs control group

Anxiety · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Selective prevention interventions vs control group

Distress/PTSD symptoms at study endpoint (higher score = higher severity) · preventing mental disorders
2 findings from 1 review