Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

4,587 questions · 5,761 findings · 495 reviews

No studies found 1,011 · 17.5%GRADE not reported 1,797 · 31.2%Very low 1,100 · 19.1%Low 1,052 · 18.3%Moderate 649 · 11.3%High 152 · 2.6%

Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.

Clear aligners (Invisalign / thermoformed aligners) vs Fixed appliances

Full-mouth bleeding score (FMBS) · Adolescents/teenagers undergoing orthodontic treatment

A single study reported a lower full-mouth bleeding score with aligners versus fixed appliances in adolescents at 12 months (MD -20.44, 95% CI -22.98 to -17.90; ungraded).

1 finding from 1 review

Ulcerative colitis (UC) vs Healthy controls without IBD

Periodontal disease (periodontitis) coincidence · Patients with ulcerative colitis (UC) and controls without IBD; adults, both sexes

Patients with ulcerative colitis have about 3-fold higher odds of periodontal disease than controls (pooled OR 3.25, 95% CI 2.23-4.74; 5 studies; ungraded).

1 finding from 1 review

Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls)

Maximal mouth opening (interincisal distance) · Adults (general and hospital populations assessed in case-control studies)

Systemic sclerosis patients have significantly reduced mouth opening compared with controls (SMD -1.06); certainty ungraded.

1 finding from 1 review

COE with vital rinsing (toluidine blue/tolonium chloride) vs Reference standard: examination and clinical evaluation by a physician/clinician with specialist knowledge or training (long-term follow-up accepted for those screened negative)

Outcome not reported · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance programme, or screened…

The review found no eligible studies for this question.

1 finding from 1 review

Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls)

Number of teeth · Adults (general and hospital populations assessed in case-control studies)

No statistically significant difference in number of teeth between SSc patients and controls (SMD -0.95, CI includes 0); certainty ungraded.

1 finding from 1 review

COE with blood/salivary (biomarker) analysis vs COE with light-based detection (e.g. ViziLite Plus, Microlux/DL, VELscope, Identafi 3000)

Outcome not reported · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance programme, or screened…

The review found no eligible studies for this question.

1 finding from 1 review