What do systematic reviews say?

Vaginal procedure vs sacral colpopexy (vault prolapse)

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 517 participants
  Low

Vaginal procedure vs sacral colpopexy (vault prolapse)

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 188 participants
  Low

Vaginal hysterectomy vs sacral hysteropexy/cervicopexy (uterine prolapse)

It is very uncertain whether vaginal hysterectomy changes awareness of prolapse compared with sacral hysteropexy/cervicopexy (uterine prolapse) (very low certainty).

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  RR 1.01 [0.1, 9.98]
  2 studies · 200 participants
  Very low

Tranexamic acid vs placebo (saline solution or sterile water)

Tranexamic acid showed no clear difference in surgical complications compared with placebo (saline solution or sterile water) (moderate certainty).

• Tranexamic acid for the reduction of bleeding during functional endoscopic sinus surgery 2023 · Cochrane Headline outcomes only
  RD 0
  2 studies · 58 participants
  Moderate

Intervention not reported

It is very uncertain whether the intervention changes hospital or 30‐day mortality (very low certainty).

• Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
  RR 0.78 [0.68, 0.91]
  190 studies · 24817 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes myocardial injury (hospital stay) (very low certainty).

• Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
  RR 1.04 [0.95, 1.14]
  86 studies · 23118 participants
  Very low

Intervention not reported

The intervention showed no clear difference in kidney injury (safety outcome) (hospital stay) (low certainty).

• Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
  RR 1.06 [0.96, 1.16]
  79 studies · 23103 participants
  Low

Intervention not reported

The intervention showed no clear difference in surgical Site Infection (hospital stay) (low certainty).

• Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
  RR 0.92 [0.83, 1.01]
  40 studies · 19368 participants
  Low

Intervention not reported

• Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
  no estimate extracted
  148 studies · 15547 participants
  Very low

Summary of findings table ‐ Remifentanil vs diazepam

• Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 50 participants
  Low

Summary of findings table ‐ Remifentanil vs diazepam

• Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 50 participants
  Low

Summary of findings table ‐ Remifentanil vs diazepam

Summary of findings table ‐ Remifentanil may leads to higher surgical assessment/satisfaction score = 1 or 2 (Technically… compared with diazepam (low certainty).

• Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
  RR 2.88 [1.6, 5.15]
  1 study · 50 participants
  Low

Summary of findings table ‐ Remifentanil vs diazepam

• Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 50 participants
  Low

Summary of findings table ‐ Remifentanil vs diazepam

Summary of findings table ‐ Remifentanil may leads to lower maternal OAA score (observer assessment of alertness/sedation) < 4… compared with diazepam (low certainty).

• Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
  RR 0.09 [0.01, 0.65]
  1 study · 50 participants
  Low

Summary of findings table ‐ Remifentanil vs diazepam

The review found no eligible studies for this question.

• Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Remifentanil vs diazepam

The review found no eligible studies for this question.

• Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

It is very uncertain whether the intervention changes BMI loss (kg/m²) (very low certainty).

• Surgery for the treatment of obesity in children and adolescents 2022 · Cochrane Headline outcomes only
  MD 11.4
  1 study · 50 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes weight loss (kg) (very low certainty).

• Surgery for the treatment of obesity in children and adolescents 2022 · Cochrane Headline outcomes only
  MD 31.6
  1 study · 50 participants
  Very low

Intervention not reported

• Surgery for the treatment of obesity in children and adolescents 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 42 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes health‐related quality of life (CHQ (8 subscores); scale 0 to 100,… (very low certainty).

• Surgery for the treatment of obesity in children and adolescents 2022 · Cochrane Headline outcomes only
  MD 16.3
  1 study · 42 participants
  Very low