Findings

What do systematic reviews say?

4,756 questions · 11,779 findings · 747 reviews · Headline outcomes only

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No studies found 3,205 · 27.2%GRADE not reported 628 · 5.3%Very low 3,261 · 27.7%Low 2,913 · 24.7%Moderate 1,453 · 12.3%High 319 · 2.7%

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Summary of findings ‐ high‐dose pancreatic enzymes vs low‐dose pancreatic enzymes

Treatment failure rate · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ high‐dose pancreatic enzymes vs low‐dose pancreatic enzymes

Adherence · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ high‐dose pancreatic enzymes vs low‐dose pancreatic enzymes

Episodes of acute DIOS · adults and children with cystic fibrosis

1 finding from 1 review

Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Summary of findings ‐ high‐dose pancreatic enzymes vs low‐dose pancreatic enzymes

Adverse effects: abdominal mass · adults and children with cystic fibrosis

1 finding from 1 review

Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Summary of findings ‐ high‐dose pancreatic enzymes vs low‐dose pancreatic enzymes

Abdominal pain · adults and children with cystic fibrosis

1 finding from 1 review

Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Topical mydriatics vs intracameral mydriatics

AE: cystoid macular edema · patients undergoing cataract surgery

Topical mydriatics showed no clear difference in AE: cystoid macular edema compared with intracameral mydriatics (low certainty).

2 findings from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 0.32 [0.01, 7.83]
1 study · 555 participants
Low
Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 0.32 [0.01, 7.83]
1 study · 555 participants
Low

Topical mydriatics vs depot delivery systems

Mean pupillary diameter—at the beginning of cataract surgery (mm) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 324 participants
Low

Topical mydriatics vs depot delivery systems

Mean pupillary diameter—at the end of cataract surgery (mm) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 210 participants
Very low

Topical mydriatics vs depot delivery systems

Intraoperative surgical time—total intraoperative time (min) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 58 participants
Very low

Topical mydriatics vs depot delivery systems

AE: vitreous loss—any time point during or after surgery · patients undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical mydriatics vs intracameral mydriatics

Mean pupillary diameter—at the beginning of cataract surgery (mm) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 242 participants
Low

Intracameral mydriatics vs depot delivery systems

Mean pupillary diameter—at the beginning of cataract surgery (mm) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Intracameral mydriatics vs depot delivery systems

Mean pupillary diameter—at the end of cataract surgery (mm) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Intracameral mydriatics vs depot delivery systems

Intraoperative surgical time—total intraoperative time (min) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Intracameral mydriatics vs depot delivery systems

Adverse events · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Topical mydriatics vs intracameral mydriatics

Mean pupillary diameter—at the end of cataract surgery (mm) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 799 participants
Low

Topical mydriatics vs intracameral mydriatics

Intraoperative surgical time—total intraoperative time (min) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 817 participants
Low

Topical mydriatics vs intracameral mydriatics

AE: posterior capsule rupture · patients undergoing cataract surgery

Topical mydriatics showed no clear difference in AE: posterior capsule rupture compared with intracameral mydriatics (low certainty).

2 findings from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 0.32 [0.01, 7.83]
1 study · 555 participants
Low
Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 0.32 [0.01, 7.83]
1 study · 555 participants
Low

Psychological interventions vs usual care

Proportion of wounds healed · adults with diabetes with current or previous foot ulceration

It is very uncertain whether psychological intervention changes proportion of wounds completely healed at 3 months compared with standard care (very low certainty).

2 findings from 1 review

Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes 2021 · Cochrane Headline outcomes only
RR 6.25
2 studies · 76 participants
Very low
Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes 2021 · Cochrane Headline outcomes only
RR 0.59
2 studies · 76 participants
Very low

Psychological interventions vs Other Psychological Interventions

Number of foot ulcer recurrences · adults with diabetes with current or previous foot ulceration

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found