Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

4,345 questions · 4,525 findings · 483 reviews

No studies found 1,024 · 22.6%GRADE not reported 388 · 8.6%Very low 1,172 · 25.9%Low 1,227 · 27.1%Moderate 576 · 12.7%High 138 · 3%

Tramadol vs pethidine

Additional analgesia required (escape analgesia) · children undergoing surgery

It is very uncertain whether tramadol changes number of patients requiring rescue analgesia (PACU) compared with pethidine (very low certainty).

1 finding from 1 review

Tramadol vs pethidine

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

Tramadol showed no clear difference in number of patients with moderate to severe pain (PACU) compared with pethidine (low certainty).

1 finding from 1 review

Tramadol vs pethidine

Number of patients with PONV (PACU) · children undergoing surgery

Tramadol showed no clear difference in number of patients with PONV (PACU) compared with pethidine (low certainty).

1 finding from 1 review

Tramadol vs fentanyl

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

The review found no eligible studies for this question.

1 finding from 1 review

Tramadol vs placebo

Number of patients with PONV (PACU) · children undergoing surgery

Tramadol showed no clear difference in number of patients with PONV (PACU) compared with placebo (moderate certainty).

1 finding from 1 review

Tramadol vs placebo

Number of patients with postoperative nausea and vomiting (24 hours postoperatively) · children undergoing surgery

Tramadol showed no clear difference in number of patients with PONV (24 hours postoperatively) compared with placebo (moderate certainty).

1 finding from 1 review

Tramadol vs morphine

Additional analgesia required (escape analgesia) · children undergoing surgery

Tramadol showed no clear difference in number of patients requiring rescue analgesia (PACU) compared with morphine (low certainty).

2 findings from 1 review

Tramadol vs morphine

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

The review found no eligible studies for this question.

1 finding from 1 review

Tramadol vs nalbuphine

Additional analgesia required (escape analgesia) · children undergoing surgery

It is very uncertain whether tramadol changes number of patients requiring rescue analgesia (24 hours… compared with nalbuphine (very low certainty).

1 finding from 1 review

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Harms arising during orthodontic treatment (gingival and periodontal problems, anchorage loss and iatrogenic damage to teeth e.g. caries/decalcification, root resorption); only periodontal/gingival health assessed · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…
1 finding from 1 review
  • SoF: Assumed risk 'See comment'; Corresponding risk 'See comment'; 13 (1 study, split‐mouth); Quality ⊕⊖⊖⊖ very low. Comment: 'Gingival and periodonal problems only were assesed in 1 study (Aboul‐Ela 2011). No precise…
    1 study · 13 participants
    Very low