What do systematic reviews say?

Summary of findings table (subcomparison 2): second‐line chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

It is very uncertain whether summary of findings table (subcomparison 2): second‐line… changes toxicity compared with control intervention alone (very low certainty).

• Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1638 participants
  Very low

Summary of findings table (subcomparison 2): second‐line chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

• Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1638 participants
  Very low

Summary of findings: figure‐of‐eight bandage vs arm sling

The review found no eligible studies for this question.

• Conservative interventions for treating middle third clavicle fractures in adolescents and adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings for exercise plus education vs control

• Interventions for preventing falls in Parkinson's disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 305 participants
  Very low

Summary of Findings Table ‐ The Lidcombe Program vs waiting list control

• Non‐pharmacological interventions for stuttering in children six years and younger 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Summary of findings for cholinesterase inhibitors vs placebo

• Interventions for preventing falls in Parkinson's disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 121 participants
  Very low

Summary of findings for the main comparison. Physical activity and exercise interventions vs usual care

• Physical activity interventions for people with congenital heart disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  14 studies · 732 participants
  Moderate

Summary of findings for the main comparison. Physical activity and exercise interventions vs usual care

• Physical activity interventions for people with congenital heart disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 163 participants
  Very low

Summary of findings for the main comparison. Physical activity and exercise interventions vs usual care

• Physical activity interventions for people with congenital heart disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 328 participants
  Low

Summary of findings for the main comparison. Physical activity and exercise interventions vs usual care

• Physical activity interventions for people with congenital heart disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 179 participants
  Moderate

Summary of findings for the main comparison. Physical activity and exercise interventions vs usual care

• Physical activity interventions for people with congenital heart disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 18 participants
  Moderate

Summary of findings for the main comparison. Physical activity and exercise interventions vs usual care

• Physical activity interventions for people with congenital heart disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 501 participants
  Moderate

Summary of findings for the main comparison. Physical activity and exercise interventions vs usual care

The review found no eligible studies for this question.

• Physical activity interventions for people with congenital heart disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings ‐ DVD plus information booklet vs information booklet alone

Summary of findings ‐ DVD plus information booklet showed no clear difference in compliance or adherence to the trial intervention (including… compared with information booklet alone (low certainty).

• Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
  RR 1.02 [0.81, 1.28]
  1 study · 108 participants
  Low

Summary of findings ‐ DVD plus information booklet vs information booklet alone

The review found no eligible studies for this question.

• Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings ‐ auto‐hypnosis (self‐hypnosis) vs control

• Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 24 participants
  Very low

Summary of findings ‐ auto‐hypnosis (self‐hypnosis) vs control

The review found no eligible studies for this question.

• Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Service system approaches vs inactive control (usual care care, attention control, waitlist)

The review found no eligible studies for this question.

• Interventions from pregnancy to two years after birth for parents experiencing complex post‐traumatic stress disorder… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Service system approaches vs inactive control (usual care care, attention control, waitlist)

• Interventions from pregnancy to two years after birth for parents experiencing complex post‐traumatic stress disorder… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 52 participants
  Low

Summary of findings table ‐ Service system approaches vs inactive control (usual care care, attention control, waitlist)

The review found no eligible studies for this question.

• Interventions from pregnancy to two years after birth for parents experiencing complex post‐traumatic stress disorder… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found