Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

407 questions · 412 findings · 45 reviews · Headline outcomes only

No studies found 137 · 33.3%GRADE not reported 8 · 1.9%Very low 129 · 31.3%Low 88 · 21.4%Moderate 47 · 11.4%High 3 · 0.7%

Isopropyl alcohol vs Normal saline

Nausea duration (nausea‐free at end of treatment) Measured by participant self‐report or medical or nursing observation · adults and children having any type of surgical procedure under general anaesthesia, regional anaesthesia or sedation, as hospital…

The review found no eligible studies for this question.

1 finding from 1 review

Isopropyl alcohol vs Normal saline

Rescue antiemetic · adults and children having any type of surgical procedure under general anaesthesia, regional anaesthesia or sedation, as hospital…

It is very uncertain whether isopropyl alcohol changes use of rescue antiemetics Assessed by proportion requiring rescue… compared with saline (very low certainty).

1 finding from 1 review

Isopropyl alcohol vs Normal saline

Adverse events (common reactions to aromatherapy include skin rashes, dyspnoea, headache, cardiac arrhythmias, hypotension, hypertension or dizziness) · adults and children having any type of surgical procedure under general anaesthesia, regional anaesthesia or sedation, as hospital…

The review found no eligible studies for this question.

1 finding from 1 review

Oropharyngeal colostrum (OPC) vs No treatment or saline or water

Any late‐onset sepsis ‐ all infants · preterm infants

It is very uncertain whether oropharyngeal colostrum (OPC) changes incidence of late‐onset sepsis compared with control (water, saline, or no intervention) (very low certainty).

1 finding from 1 review

Ear drops (any active treatment) vs ear drops (water or saline)

Proportion of patients (or ears) with complete clearance of ear wax · adults and children with ear wax requiring removal

Ear drops (any active treatment) may leads to higher proportion of patients (or ears) with complete clearance of ear wax compared with ear drops (water or saline) (low certainty).

1 finding from 1 review