Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

949 questions · 1,008 findings · 130 reviews · Gynaecology and Fertility

No studies found 195 · 19.3%GRADE not reported 30 · 3%Very low 346 · 34.3%Low 323 · 32%Moderate 101 · 10%High 13 · 1.3%

Gonadotrophins with anti‐oestrogens vs gonadotropins alone

Clinical pregnancy rate · intrauterine insemination (IUI) in women with infertility

It is very uncertain whether gonadotrophins with anti‐oestrogens changes clinical pregnancy rate per couple compared with gonadotropins alone (very low certainty).

1 finding from 1 review

Aromatase inhibitors with gonadotropins vs anti‐oestrogens with gonadotropins

Multiple pregnancy rate · intrauterine insemination (IUI) in women with infertility

Aromatase inhibitors with gonadotropins showed no clear difference in multiple pregnancy rate per couple compared with anti‐oestrogens with gonadotropins (low certainty).

1 finding from 1 review

Aromatase inhibitors with gonadotropins vs anti‐oestrogens with gonadotropins

Clinical pregnancy rate · intrauterine insemination (IUI) in women with infertility

It is very uncertain whether aromatase inhibitors with gonadotropins changes clinical pregnancy rate per couple compared with anti‐oestrogens with gonadotropins (very low certainty).

1 finding from 1 review

Chinese herbal medicine (CHM) + follicle aspiration + ovulation induction vs follicle aspiration + ovulation induction

Adverse event ‐ multiple pregnancy · subfertile women with PCOS

It is very uncertain whether chinese herbal medicine (CHM) plus follicle aspiration plus… changes multiple pregnancy (adverse events) compared with follicle aspiration plus ovulation induction (very low certainty).

1 finding from 1 review

Chinese herbal medicine (CHM) + follicle aspiration + ovulation induction vs follicle aspiration + ovulation induction

Pregnancy rate · subfertile women with PCOS

It is very uncertain whether chinese herbal medicine (CHM) plus follicle aspiration plus… changes pregnancy rate compared with follicle aspiration plus ovulation induction (very low certainty).

1 finding from 1 review

Endometrial injury vs control

Clinical pregnancy · women undergoing assisted reproduction

Endometrial injury showed no clear difference in clinical pregnancy per woman randomised (studies at low risk of… compared with control (moderate certainty).

2 findings from 1 review

Endometrial injury vs control

Clinical pregnancy per woman randomised: sensitivity analysis (no high‐risk) · women undergoing assisted reproduction

Endometrial injury showed no clear difference in clinical pregnancy per woman randomised: sensitivity analysis (no… compared with control (low certainty).

1 finding from 1 review

Raloxifene vs placebo

Adverse events ‐ depression · women with endometriosis, following complete surgical excision of lesions

It is very uncertain whether raloxifene changes adverse events ‐ depression compared with placebo (very low certainty).

1 finding from 1 review