Cochrane · systematic review · CD007677
Pentoxifylline for the treatment of endometriosis‐associated pain and infertility
Grammatis, AL, Georgiou, EX, Becker, CM · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
6
No studies
5
Included studies
NR
No studies 5 · 45.5%Ungraded 0 · 0%Very low 6 · 54.5%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsPentoxifylline compared to placebo in women with endometriosis
Population: women with endometriosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth rate  Pentoxifylline vs placebo | no estimate extracted | NR | No studies |
Overall pain Pentoxifylline vs placebo | no estimate extracted | NR | No studies |
Clinical pregnancy rate Pentoxifylline vs placebo | RR 1.38 [0.91, 2.1] | 3 studies · 285 participants | Very low Downgraded: risk of bias, imprecision |
Miscarriage rate Pentoxifylline vs placebo | Peto OR 1.99 [0.2, 19.37] | 2 studies · 164 participants | Very low Downgraded: risk of bias, imprecision |
Recurrence rate of endometriosis Pentoxifylline vs placebo | RR 0.84 [0.3, 2.36] | 1 study · 121 participants | Very low Downgraded: risk of bias, imprecision |
Adverse events Pentoxifylline vs placebo | no estimate extracted | NR | No studies |
Pentoxifylline compared to no treatment in women with endometriosis
Population: women with endometriosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth rate Pentoxifylline vs no treatment | no estimate extracted | NR | No studies |
Overall pain ‐ 1 month Pentoxifylline vs no treatment | no estimate extracted | 1 study · 34 participants | Very low Downgraded: risk of bias, imprecision |
Overall pain ‐ 2 months Pentoxifylline vs no treatment | no estimate extracted | 1 study · 34 participants | Very low Downgraded: risk of bias, imprecision |
Overall pain ‐ 3 months Pentoxifylline vs no treatment | no estimate extracted | 1 study · 34 participants | Very low Downgraded: risk of bias, imprecision |
Adverse events Pentoxifylline vs no treatment | no estimate extracted | NR | No studies |