What do systematic reviews say?

Statins vs control

The review found no eligible studies for this question.

• Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Beta‐agonist vs control

• Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 606 participants
  Very low

Corticosteroids vs control

The review found no eligible studies for this question.

• Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Iron vs placebo

Iron showed no clear difference in withdrew to use other RLS medication or because of inadequate RLS… compared with placebo (low certainty).

• Iron for the treatment of restless legs syndrome 2019 · Cochrane Headline outcomes only
  RR 0.77 [0.41, 1.47]
  9 studies · 391 participants
  Low

Low dialysate [Na+] (< 138 mM) vs neutral dialysate [Na+] (138 to 140 mM)

• Low dialysate sodium levels for chronic haemodialysis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 103 participants
  Low

Low dialysate [Na+] (< 138 mM) vs high dialysate [Na+] (> 140 mM)

The review found no eligible studies for this question.

• Low dialysate sodium levels for chronic haemodialysis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Low dialysate [Na+] (< 138 mM) vs neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (> 140 mM)

• Low dialysate sodium levels for chronic haemodialysis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 103 participants
  Low

Ceftriaxone vs penicillin G

• Antibiotic therapy for adults with neurosyphilis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1 participants
  Very low

Intraperitoneal lidocaine instillation vs IM morphine

Intraperitoneal lidocaine instillation may leads to lower number of women requiring rescue medication compared with intramuscular morphine (low certainty).

• Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
  RR 0.22 [0.09, 0.54]
  Studies not reported
  Low

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs placebo

Combination of intraperitoneal lidocaine instillation and… may leads to lower number of women requiring rescue medication compared with placebo (low certainty).

• Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
  RR 0.11 [0.03, 0.42]
  Studies not reported
  Low

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs lidocaine intraperitoneal instillation alone

Combination of lidocaine intraperitoneal instillation plus… showed no clear difference in number of women requiring rescue medication compared with lidocaine intraperitoneal instillation alone (low certainty).

• Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
  RR 0.5 [0.1, 2.43]
  Studies not reported
  Low

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs IM morphine

Combination of lidocaine intraperitoneal instillation plus… may leads to lower number of women requiring rescue medication compared with intramuscular morphine alone (low certainty).

• Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
  RR 0.11 [0.03, 0.42]
  Studies not reported
  Low

EMLA vs placebo

EMLA cream may leads to lower number of women requiring rescue medication compared with placebo (low certainty).

• Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
  RR 0.36 [0.25, 0.53]
  Studies not reported
  Low

Lidocaine instillation vs placebo

Lidocaine instillation may leads to lower number of women requiring rescue medication compared with placebo (low certainty).

• Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
  RR 0.27 [0.17, 0.44]
  Studies not reported
  Low

Intramuscular morphine vs placebo

Intramuscular morphine showed no clear difference in number of women requiring rescue medication compared with placebo (low certainty).

• Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
  RR 1 [0.81, 1.23]
  Studies not reported
  Low

Cetirizine 10 mg/d vs placebo (4‐week intervention)

• Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 84 participants
  Low

Fexofenadine 120 mg/d vs placebo (1‐week intervention)

• Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1 participants
  Moderate

Loratadine 10 mg vs placebo (4‐week intervention)

The review found no eligible studies for this question.

• Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Loratadine 10 mg vs placebo (2‐week intervention)

The review found no eligible studies for this question.

• Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Cetirizine 0.5 mg/kg/d vs placebo (18‐month intervention)

• Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 795 participants
  Moderate