Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,355 questions · 2,459 findings · 279 reviews

No studies found 556 · 22.6%GRADE not reported 490 · 19.9%Very low 593 · 24.1%Low 479 · 19.5%Moderate 243 · 9.9%High 98 · 4%

Hypnosis vs No hypnosis (no hypnotic intervention)

Physiological measures during local anaesthesia (pulse rate and oxygen saturation) · Children aged 4 to 13 years with no previous dental experience undergoing restorative treatment with local anaesthesia (Gokli 1994)
1 finding from 1 review
  • With regard to oxygen saturation and pulse rate, only pulse rate was significantly lower in the hypnosis group (P = 0.005); oxygen saturation did not differ significantly. (Gokli 1994; cross-over, 29 children.)
    1 study · 29 participants
    GRADE not reported

Hypnosis vs No hypnosis (no hypnotic intervention)

Measures of behaviour during local anaesthesia administration (undesirable behaviours: crying, hand movement, physical resistance, leg movement) · Children aged 4 to 13 years with no previous dental experience undergoing restorative treatment with local anaesthesia (Gokli 1994)
1 finding from 1 review
  • Patients who were hypnotised demonstrated fewer undesirable behaviours (crying, hand movement, physical resistance and leg movement) than those who did not undergo hypnosis. Decreased crying with hypnosis was the only…
    1 study · 29 participants
    GRADE not reported

Any anti‐adhesion therapy vs placebo or no treatment following operative hysteroscopy

Live birth · women treated by operative hysteroscopy for uterine pathology associated with subfertility or adverse pregnancy outcome

It is very uncertain whether any anti‐adhesion therapy changes live birth a compared with placebo or no treatment following operative hysteroscopy (very low certainty).

1 finding from 1 review

Thoracic epidural anaesthesia vs conventional pain control

Persistent pain 3 to 18 months after thoracotomy (We defined persistent postsurgical pain as new pain that did not exist before the operation, measured using differences in scores based on validated pain scales; patient interview between 3 to 18 m... · Patients undergoing thoracotomy

Thoracic epidural anaesthesia probably leads to lower persistent pain 3 to 18 months after thoracotomy (We defined… compared with conventional pain control (moderate certainty).

1 finding from 1 review

Maintenance anaesthesia: inhalational vs intravenous

Nausea and vomiting ‐ subgroup analysis: thiopentone or halothane + N2O versus propofol or propofol + N2O · paediatric

Maintenance anaesthesia: inhalational may leads to higher nausea and vomiting ‐ subgroup analysis: thiopentone or halothane +… compared with intravenous (low certainty).

2 findings from 1 review

Adhesive precoated (APC) flash-free brackets (minimal excess adhesive) vs Conventional ceramic brackets

Enamel demineralization (DIAGNOdent score) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

Adhesive precoated flash-free brackets showed no demineralization difference, with certainty not graded.

1 finding from 1 review

Bonded molar tubes (attached with adhesive) vs Molar bands (cemented, e.g. with glass ionomer cement)

Decalcification · Participants with full arch fixed orthodontic appliance(s) with molar tubes bonded to first or second permanent molars; excludes prior…

Bonded molar tubes (attached with adhesive) led to higher decalcification (participant level) compared with molar bands (cemented, e.g. with glass ionomer cement); GRADE not reported.

1 finding from 1 review

Bonded molar tubes (attached with adhesive) vs Molar bands (cemented, e.g. with glass ionomer cement)

First time failure at participant level · Participants with full arch fixed orthodontic appliance(s) with molar tubes bonded to first or second permanent molars; excludes prior…

Bonded molar tubes (attached with adhesive) led to higher first time failure at participant level compared with molar bands (cemented, e.g. with glass ionomer cement); GRADE not reported.

1 finding from 1 review

Bonded molar tubes (attached with adhesive) vs Molar bands (cemented, e.g. with glass ionomer cement)

First time failure at tooth level · Participants with full arch fixed orthodontic appliance(s) with molar tubes bonded to first or second permanent molars; excludes prior…

Bonded molar tubes (attached with adhesive) led to higher first time failure at tooth level compared with molar bands (cemented, e.g. with glass ionomer cement); GRADE not reported.

1 finding from 1 review

One-step adhesive bonding system (GC Ortho Connect) vs Conventional three-step bonding system (3M Transbond XT)

White spot lesion incidence, area, and depth · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

GC Ortho Connect had more frequent, larger, and deeper WSLs, with certainty not graded.

1 finding from 1 review

Indirect bonding using flowable composite adhesive (Opal Bond MV) vs Direct bonding (conventional, Transbond XT)

White spot lesion formation (QLF: fluorescence loss, lesion area) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

Indirect bonding with a flowable adhesive favored less QLF-measured demineralization, with certainty not graded.

1 finding from 1 review