Cochrane · systematic review · CD009015
Intravenous versus inhalational anaesthesia for paediatric outpatient surgery
Ortiz, AC, Atallah, ÁN, Matos, D, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 40%Low 3 · 60%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Induction and maintenance: sevoflurane + nitrous oxide (N2O) compared to propofol + N2O for paediatric outpatient surgery
Population: paediatric
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Postoperative nausea and vomiting Induction and maintenance: sevoflurane + nitrous oxide (N2O) vs propofol + N2O | OR 2.96 [1.35, 6.49] | 4 studies · 176 participants | Low Downgraded: risk of bias, imprecision |
Postoperative behavioural disturbances Different scales Induction and maintenance: sevoflurane + nitrous oxide (N2O) vs propofol + N2O | OR 2.67 [1.14, 6.23] | 4 studies · 176 participants | Very low Downgraded: risk of bias, imprecision |
Intraoperative and postoperative respiratory and cardiovascular complications Induction and maintenance: sevoflurane + nitrous oxide (N2O) vs propofol + N2O | OR 0.75 [0.27, 2.13] | 3 studies · 130 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Maintenance anaesthesia: inhalational compared to intravenous for paediatric outpatient surgery
Population: paediatric
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Nausea and vomiting ‐ subgroup analysis: thiopentone or halothane + N2O versus propofol or propofol + N2O Maintenance anaesthesia: inhalational vs intravenous | OR 3.23 [1.49, 7.02] | 4 studies · 176 participants | Low Downgraded: risk of bias |
Nausea and vomiting ‐ subgroup analysis: thiopentone or halothane + N2O versus propofol or propofol + N2O Maintenance anaesthesia: inhalational vs intravenous | OR 7.44 [2.6, 21.26] | 2 studies · 87 participants | Low Downgraded: risk of bias |