Anti‐epileptic drugs showed no clear difference in early seizure Counts of events compared with other anti‐epileptic drugs (low certainty).
Neuroprotective agent showed no clear difference in early seizure Count of events compared with placebo (low certainty).
SPECIALISED TEAM probably leads to lower compliance with treatment ‐ treatment stopped in spite of need ‐ by… compared with STANDARD CARE (moderate certainty).
SPECIALISED TEAM showed no clear difference in compliance with treatment ‐ treatment stopped in spite of need ‐ by… compared with STANDARD CARE (moderate certainty).
Beta‐blockers showed no clear difference in global state: 1. Leaving the study early ‐ Short term compared with placebo (low certainty).
OFS leads to lower overall survival (OS) Median compared with no OFS (high certainty).
OFS leads to lower disease‐free survival (DFS) Median compared with no OFS (high certainty).
OFS may leads to higher toxicity ‐ hot flushes (a combination of "grade 3/4" and "any grade"… compared with no OFS (low certainty).
OFS may leads to higher toxicity ‐ bone health (osteoporosis defined by a T score < ‐2.5) compared with no OFS (low certainty).
OFS probably leads to lower contralateral breast cancer compared with no OFS (moderate certainty).
Vaginal misoprostol may leads to higher complete miscarriage compared with placebo (low certainty).
Vaginal misoprostol may leads to higher nausea compared with surgical evacuation of uterus (low certainty).
Vaginal misoprostol may leads to higher diarrhoea compared with surgical evacuation of uterus (low certainty).
Vaginal misoprostol may leads to higher pain relief compared with surgical evacuation of uterus (low certainty).
Vaginal misoprostol showed no clear difference in woman’s satisfaction/acceptability of method compared with surgical evacuation of uterus (low certainty).
The review found no eligible studies for this question.
Vaginal misoprostol showed no clear difference in nausea compared with placebo (low certainty).
Vaginal misoprostol showed no clear difference in diarrhoea compared with placebo (low certainty).