Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

339 questions · 346 findings · 42 reviews · Headline outcomes only

No studies found 74 · 21.4%GRADE not reported 8 · 2.3%Very low 72 · 20.8%Low 107 · 30.9%Moderate 68 · 19.7%High 17 · 4.9%

Intervention not reported

Social confidence, social inclusion, social networks or personalised quality of life measures ‐ no clinically significant change · people with antipsychotic‐induced tardive dyskinesia

The review found no eligible studies for this question.

1 finding from 1 review

Flunarizine vs placebo

Adverse effects ‐ Blurred vision No of patients with blurred vision · patients with drug‐resistant epilepsy

Flunarizine showed no clear difference in adverse effects ‐ Blurred vision No of patients with blurred vision compared with placebo (high certainty).

1 finding from 1 review

Nimodipine vs placebo

50% or greater reduction in seizure frequency Number of seizures · patients with drug‐resistant epilepsy

Nimodipine showed no clear difference in 50% or greater reduction in seizure frequency Number of seizures compared with placebo (moderate certainty).

1 finding from 1 review