Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

3,454 questions · 3,562 findings · 816 reviews · Headline outcomes only

No studies found 538 · 15.1%GRADE not reported 239 · 6.7%Very low 933 · 26.2%Low 1,041 · 29.2%Moderate 612 · 17.2%High 199 · 5.6%

Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters

All‐cause blood stream infection (during hospitalisation) · any patient requiring a PIVC expected to remain in‐situ for at least 3 days

Effects of clinically‐indicated replacement showed no clear difference in all‐cause blood stream infection (during hospitalisation) compared with routine change of peripheral intravenous catheters (moderate certainty).

1 finding from 1 review

Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters

Infiltration (during hospitalisation) · any patient requiring a PIVC expected to remain in‐situ for at least 3 days

Effects of clinically‐indicated replacement probably leads to higher infiltration (during hospitalisation) compared with routine change of peripheral intravenous catheters (moderate certainty).

1 finding from 1 review

Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters

Catheter blockage (during hospitalisation) · any patient requiring a PIVC expected to remain in‐situ for at least 3 days

Effects of clinically‐indicated replacement probably leads to higher catheter blockage (during hospitalisation) compared with routine change of peripheral intravenous catheters (moderate certainty).

1 finding from 1 review

Perioperative alcohol cessation intervention vs treatment

Postoperative complications after perioperative intervention (e.g. wound‐related complications, secondary surgery, cardiopulmonary complications, admission to intensive care) defined by need for treatment · adult surgical patients consuming 3 or more units of alcohol per day

Perioperative alcohol cessation intervention probably leads to lower postoperative complications after perioperative intervention (e.g.… compared with treatment (moderate certainty).

1 finding from 1 review

Perioperative alcohol cessation intervention vs treatment

Successful quitters (number of abstainers) at the end of the programme (with or without validation by interview, breath test, or alcohol markers) · adult surgical patients consuming 3 or more units of alcohol per day

Perioperative alcohol cessation intervention probably leads to higher successful quitters (number of abstainers) at the end of the… compared with treatment (moderate certainty).

1 finding from 1 review

Other prokinetics vs domperidone

Adverse events · patients with functional dyspepsia

It is very uncertain whether other prokinetics changes adverse events compared with domperidone 10mg three times a day (very low certainty).

1 finding from 1 review

Intervention not reported

Heparin‐induced thrombocytopenia (HIT) · people undergoing surgical procedures and treated with UFH or LMWH for prophylaxis of thrombotic events lasting at least 5 days

The intervention may leads to lower heparin‐induced thrombocytopenia (HIT) (low certainty).

1 finding from 1 review

Intervention not reported

HIT in people undergoing major surgical procedures · people undergoing surgical procedures and treated with UFH or LMWH for prophylaxis of thrombotic events lasting at least 5 days

The intervention may leads to lower HIT in people undergoing major surgical procedures (low certainty).

1 finding from 1 review

Intervention not reported

HIT complicated by venous thromboembolism · people undergoing surgical procedures and treated with UFH or LMWH for prophylaxis of thrombotic events lasting at least 5 days

The intervention may leads to lower HIT complicated by venous thromboembolism (low certainty).

1 finding from 1 review

Intervention not reported

Motor development and vigor (MDV) domain of the NAPI tool Normative mean and SD at 36 weeks PMA 63 (14.5) Higher scores are associated with more mature behaviour (Snider 2005) · neonates with pain associated with potentially painful procedures for 7 days
1 finding from 1 review

Intervention not reported

Alertness and orientation (AO) domain of the NAPI tool Normative mean and SD at 36 weeks PMA 54 (19.4) Higher scores are associated with more mature behaviour (Snider 2005) · neonates with pain associated with potentially painful procedures for 7 days
1 finding from 1 review

Intervention not reported

Pain intensity (VAS) short term · patients with chronic mechanical neck pain (pain for more than 90 days)
1 finding from 1 review