Quality of life · adults aged 18 years and above with diagnosis of non‐cystic fibrosis bronchiectasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Exacerbations · adults with bronchiectasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse events · adults with bronchiectasis
1 finding from 1 review
Complete clearance · people with scabies, 2 to 80 years of ageLocation: India, Pakistan
Oral ivermectin 200 μg/kg (1 to 3 doses) may leads to lower complete clearance ‐ week 1 compared with topical permethrin 5% cream (1 to 3 applications) (low certainty).
5 findings from 1 review
RR 0.65 [0.54, 0.78]
6 studies · 613 participants
Low
RR 0.91 [0.76, 1.08]
5 studies · 459 participants
Low
RR 1 [0.86, 1.16]
1 study · 80 participants
High
Show 2 more findings
Complete clearance · people with scabies, 5 to 60 years of ageLocation: Egypt, Pakistan
Oral ivermectin 200 μg/kg (1 to 2 doses) showed no clear difference in complete clearance ‐ week 1 ‐ IVER 1 dose versus PER on 5… compared with topical permethrin 5% lotion (1 to 5 applications) (low certainty).
4 findings from 1 review
RR 0.7 [0.47, 1.03]
1 study · 107 participants
Low
RR 1 [0.78, 1.29]
1 study · 120 participants
Low
RR 0.97 [0.81, 1.17]
1 study · 107 participants
Moderate
Show 1 more finding
Number of participants with ≥ 1 AE ‐ week 2 ‐ IVER 2 doses versus PER on 5 consecutive nights · people with scabies, 5 to 60 years of ageLocation: Egypt, Pakistan
It is very uncertain whether oral ivermectin 200 μg/kg (1 to 2 doses) changes number of participants with ≥ 1 AE ‐ week 2 ‐ IVER 2 doses versus… compared with topical permethrin 5% lotion (1 to 5 applications) (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · people with scabies, 5 to 60 years of ageLocation: Egypt, Pakistan
1 finding from 1 review
Complete clearance · people with scabies, 5 to 80 years of ageLocation: Egypt, India
Oral ivermectin 200 μg/kg (1 to 3 doses) showed no clear difference in complete clearance ‐ week 1 compared with topical ivermectin 1% lotion/solution (1 to 3 applications) (low certainty).
3 findings from 1 review
RR 0.84 [0.65, 1.08]
1 study · 62 participants
Low
RR 1 [0.94, 1.06]
1 study · 62 participants
Moderate
RR 0.99 [0.95, 1.03]
2 studies · 272 participants
Moderate
Number of participants with ≥ 1 AE ‐ week 4 · people with scabies, 5 to 80 years of ageLocation: Egypt, India
It is very uncertain whether oral ivermectin 200 μg/kg (1 to 3 doses) changes number of participants with ≥ 1 AE ‐ week 4 compared with topical ivermectin 1% lotion/solution (1 to 3 applications) (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · people with scabies, 5 to 80 years of ageLocation: Egypt, India
1 finding from 1 review
Complete clearance · people with scabies, 5 to 80 years of ageLocation: India
Topical ivermectin 1% lotion (1 to 3 applications) showed no clear difference in complete clearance ‐ week 4 compared with topical permethrin 5% cream (1 to 3 applications) (moderate certainty).
1 finding from 1 review
Number of participants with ≥ 1 AE ‐ week 4 · people with scabies, 5 to 80 years of ageLocation: India
It is very uncertain whether topical ivermectin 1% lotion (1 to 3 applications) changes number of participants with ≥ 1 AE ‐ week 4 compared with topical permethrin 5% cream (1 to 3 applications) (very low certainty).
1 finding from 1 review
Complete clearance · people with scabies, over 5 years of ageLocation: India
Oral ivermectin 200 μg/kg (1 dose) showed no clear difference in complete clearance ‐ week 4 compared with oral ivermectin 200 μg/kg (2 doses) (high certainty).
1 finding from 1 review
1Sharma 2011. · people with scabies, over 5 years of ageLocation: India
1 finding from 1 review
no estimate extracted
1 participants
GRADE not reported
Number of participants with ≥ 1 AE ‐ week 2 · people with scabies, 2 to 80 years of ageLocation: India, Pakistan
1 finding from 1 review
Number of participants with ≥ 1 AE ‐ week 4 · people with scabies, 2 to 80 years of ageLocation: India, Pakistan
Oral ivermectin 200 μg/kg (1 to 3 doses) showed no clear difference in number of participants with ≥ 1 AE ‐ week 4 compared with topical permethrin 5% cream (1 to 3 applications) (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · people with scabies, 2 to 80 years of ageLocation: India, Pakistan
1 finding from 1 review
Major bleeding, requiring transfusion of packed red blood cells · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… showed no clear difference in major bleeding requiring transfusion of packed red blood cells compared with placebo (placebo solution/mouthwash); GRADE not reported.
1 finding from 1 review
Number of immediate (less than 24 hours) and delayed (24 hours to 10 days) postoperative bleeding episodes requiring intervention · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… led to lower number of immediate and delayed postoperative bleeding episodes… compared with placebo (placebo solution/mouthwash); GRADE not reported.
1 finding from 1 review
Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)
Twin Block functional appliance (conventional) showed no clear difference in final overjet compared with modified Twin Block appliances; GRADE not reported.
1 finding from 1 review