Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,049 questions in 79 reviews · Dementia and Cognitive Improvement

current versions
No studies 240 · 22.9%Ungraded 31 · 3%Very low 216 · 20.6%Low 253 · 24.1%Moderate 238 · 22.7%High 71 · 6.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
TongXingLuo vs Western medicine
Behaviour ‐ only measured in one study · People with vascular dementia
Traditional Chinese herbal medicine for vascular dementia (2018) · Cochrane
no estimate extractedNRNo studies
FuFangHaiShe vs 'no treatment'
Cognition‐MMSE · People with vascular dementia
Traditional Chinese herbal medicine for vascular dementia (2018) · Cochrane
no estimate extracted2 studies · 110 participantsLow
FuFangHaiShe vs 'no treatment'
Cognition‐HDS ‐ not measured · People with vascular dementia
Traditional Chinese herbal medicine for vascular dementia (2018) · Cochrane
no estimate extractedNRNo studies
Summary of findings table: Art therapy vs active control group activity
Change in MMSE · people with dementia
Art therapy for people with dementia (2018) · Cochrane
no estimate extracted1 study · 39 participantsVery low
Summary of findings table: Art therapy vs active control group activity
Change in Apathy Scale · people with dementia
Art therapy for people with dementia (2018) · Cochrane
no estimate extracted1 study · 39 participantsVery low
Summary of findings table: Art therapy vs active control group activity
Change in CSDD · people with dementia
Art therapy for people with dementia (2018) · Cochrane
no estimate extracted1 study · 21 participantsVery low
Summary of findings table: Art therapy vs active control group activity
Change in MCS‐8 · people with dementia
Art therapy for people with dementia (2018) · Cochrane
no estimate extracted1 study · 39 participantsVery low
Summary of findings table: Art therapy vs active control group activity
Adverse effects · people with dementia
Art therapy for people with dementia (2018) · Cochrane
no estimate extracted2 studies · 60 participantsVery low
Nectar thick liquids (300 cPs) vs regular liquids 15cPs
Elimination of aspiration on videofluoroscopy · adults with dementia and dysphagia
Modifying the consistency of food and fluids for swallowing difficulties in dementia (2018) · Cochrane
no estimate extracted1 study · 351 participantsLow
Honey thick liquids (3000 cPs) vs regular liquids (15cPs)
Elimination of aspiration on videofluoroscopy · adults with dementia and dysphagia
Modifying the consistency of food and fluids for swallowing difficulties in dementia (2018) · Cochrane
no estimate extracted1 study · 351 participantsLow
Regular fluids (15cPs) and chin down head posture vs regular fluids (15cPs) and neutral head position
Elimination of aspiration on videofluoroscopy · adults with dementia and dysphagia
Modifying the consistency of food and fluids for swallowing difficulties in dementia (2018) · Cochrane
no estimate extracted1 study · 351 participantsLow
Summary of findings for additional food items between meals vs usual care
Food and fluid intake, measured by calories consumed in total per day (kcal, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 42 participantsVery low
Summary of findings for education and nutrition promotion programme vs no intervention
Mealtime behaviour, measured by the EBS (range 0‐30, higher=better, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 656 participantsModerate
Summary of findings for spaced retrieval combined with errorless learning training programme for people with dementia vs spaced retrieval only training programme
Food and fluid intake, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 60 participantsVery low
Summary of findings for spaced retrieval combined with errorless learning training programme for people with dementia vs spaced retrieval only training programme
Nutritional status not measured · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extractedNRNo studies
Summary of findings for spaced retrieval combined with errorless learning training programme for people with dementia vs spaced retrieval only training programme
Mealtime behaviour not measured · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extractedNRNo studies
Summary of findings for spaced retrieval combined with errorless learning training programme for people with dementia vs spaced retrieval only training programme
CI: confidence interval · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extractedNRNo studies
Summary of findings for spaced retrieval training programme for people with dementia vs no intervention
Food and fluid intake, measured by amount of served food eaten (percentage, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 54 participantsVery low
Summary of findings for spaced retrieval training programme for people with dementia vs no intervention
Nutritional status, measured by MNA (range 0‐30, higher = better, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 54 participantsVery low
Summary of findings for spaced retrieval training programme for people with dementia vs no intervention
Nutritional status, measured by BMI (kg/m², · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 33 participantsVery low
Summary of findings for spaced retrieval training programme for people with dementia vs no intervention
Nutritional status, measured by body weight (kg, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 33 participantsVery low
Summary of findings for spaced retrieval training programme for people with dementia vs no intervention
Mealtime behaviour, measured by EdFED scale (range 0‐20, lower = better, 8 weeks) · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 54 participantsVery low
Summary of findings for additional food items between meals vs usual care
Nutritional status, measured by body weight (kg, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 42 participantsVery low
Summary of findings for Montessori‐based activities training programme for people with dementia vs no intervention
Food and fluid intake, measured by amount of served food eaten (percentage, 3 months) · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 54 participantsVery low
Summary of findings for Montessori‐based activities training programme for people with dementia vs no intervention
Nutritional status · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 54 participantsVery low
Summary of findings for Montessori‐based activities training programme for people with dementia vs no intervention
Nutritional status · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 33 participantsVery low
Summary of findings for Montessori‐based activities training programme for people with dementia vs no intervention
Nutritional status · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 33 participantsVery low
Summary of findings for Montessori‐based activities training programme for people with dementia vs no intervention
Mealtime behaviour · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 54 participantsVery low
Summary of findings for feeding skills training programme for nurses vs no intervention
Food and fluid intake, measured as amount of served food eaten (percentage, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 20 participantsVery low
Summary of findings for feeding skills training programme for nurses vs no intervention
Nutritional status not measured · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extractedNRNo studies
Summary of findings for feeding skills training programme for nurses vs no intervention
Mealtime behaviour, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 20 participantsVery low
Summary of findings for verbal and physical encouragement by touch vs only verbal encouragement during meals
Food and fluid intake, measured by calories consumed per meal (kcal, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 42 participantsLow
Summary of findings for verbal and physical encouragement by touch vs only verbal encouragement during meals
Food and fluid intake, measured by protein consumed per meal (grams, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 42 participantsLow
Summary of findings for additional food items between meals vs usual care
Mealtime behaviour not measured · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extractedNRNo studies
Summary of findings for verbal and physical encouragement by touch vs only verbal encouragement during meals
Nutritional status not measured · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extractedNRNo studies
Summary of findings for verbal and physical encouragement by touch vs only verbal encouragement during meals
Mealtime behaviour not measured · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extractedNRNo studies
Summary of findings for education and nutrition promotion programme vs no intervention
Food and fluid intake, measured by total protein intake (g/kg of body weight, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 78 participantsLow
Summary of findings for education and nutrition promotion programme vs no intervention
Nutritional status, measured by MNA (range 0‐30, higher = better, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 656 participantsLow
Summary of findings for education and nutrition promotion programme vs no intervention
Nutritional status, measured by BMI (kg/m², · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 52 participantsLow
Summary of findings for education and nutrition promotion programme vs no intervention
Nutritional status, measured by BMI (kg/m², · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted2 studies · 734 participantsModerate
Summary of findings for education and nutrition promotion programme vs no intervention
Nutritional status, measured by body weight (kg, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 52 participantsLow
Summary of findings for education and nutrition promotion programme vs no intervention
Nutritional status, measured by body weight (kg, · people with dementia
Environmental and behavioural modifications for improving food and fluid intake in people with dementia (2018) · Cochrane
no estimate extracted1 study · 656 participantsModerate
B vitamins vs placebo
Incidence of dementia ‐ not measured · MCI
Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with… (2018) · Cochrane
no estimate extractedNRNo studies
Vitamin E vs placebo
Episodic memory · MCI
Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with… (2018) · Cochrane
no estimate extracted1 study · 1 participantsLow
Vitamin E vs placebo
Executive functioning · MCI
Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with… (2018) · Cochrane
no estimate extracted1 study · 1 participantsLow
Vitamin E vs placebo
Quality of life ‐ not measured · MCI
Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with… (2018) · Cochrane
no estimate extractedNRNo studies
Vitamin E vs placebo
Mortality · MCI
Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with… (2018) · Cochrane
no estimate extracted1 study · 1 participantsUngraded
Vitamin E + vitamin C vs placebo
Incidence of dementia ‐ not measured · MCI
Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with… (2018) · Cochrane
no estimate extractedNRNo studies
Vitamin E + vitamin C vs placebo
Overall cognitive function · MCI
Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with… (2018) · Cochrane
no estimate extracted1 study · 256 participantsVery low
Vitamin E + vitamin C vs placebo
Episodic memory ‐ not measured · MCI
Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with… (2018) · Cochrane
no estimate extractedNRNo studies