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Evidence found and GRADE certainty

550 questions · 581 findings · 23 reviews · Implants and prosthodontics

No studies found 87 · 15%GRADE not reported 388 · 66.8%Very low 88 · 15.1%Low 10 · 1.7%Moderate 8 · 1.4%High 0 · 0%

Hyperbaric oxygen vs No HBO therapy

Cost‐effectiveness · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

The review found no eligible studies for this question.

1 finding from 1 review

Hyperbaric oxygen vs No HBO therapy

Implant failure · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

Hyperbaric oxygen (HBO) therapy showed no clear difference in implant failure compared with no HBO therapy; GRADE not reported.

1 finding from 1 review

Hyperbaric oxygen vs No HBO therapy

Postimplantation complications · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

Hyperbaric oxygen (HBO) therapy showed no clear difference in postimplantation complications compared with no HBO therapy; GRADE not reported.

1 finding from 1 review

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Implant failure · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) probably leads to lower implant failure compared with no antibiotics or placebo (moderate certainty).

1 finding from 1 review

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Adverse events · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in adverse events compared with no antibiotics or placebo; GRADE not reported.

1 finding from 1 review

Implant surface smoothening added to systemic antibiotics + resective surgery + local antibiotics vs No implant surface smoothening (same surgical protocol)

Implant failure · People with at least one dental implant affected by perimplantitis

Implant surface smoothening added to systemic antibiotics +… showed no clear difference in implant failure compared with no implant surface smoothening (same surgical protocol); GRADE not reported.

1 finding from 1 review

Non-surgical interventions vs Surgical interventions

Outcome not reported · People with at least one dental implant affected by peri-implantitis

The review found no eligible studies for this question.

1 finding from 1 review

Low-gold (Midas) or silver-palladium (Albacast) alloy FDP vs High-gold content control alloy (JS C) FDP

Visual marginal discrepancy (3 years) · Patients receiving single crowns and FDPs; split-mouth

Low-gold (Midas) or silver-palladium (Albacast) alloy FDP showed no clear difference in visual marginal discrepancy (3 years) compared with high-gold content control alloy (JS C) FDP; GRADE not reported.

1 finding from 1 review

Fixed dental prosthesis (cantilever FDP) vs Removable dental prosthesis (RDP)

Incidence-free survival (caries, endodontic treatment, tooth loss) · Patients with a shortened dental arch (missing posterior teeth)

Fixed dental prosthesis (cantilever FDP) showed no clear difference in incidence-free survival (caries, endodontic treatment, tooth loss) compared with removable dental prosthesis (RDP); GRADE not reported.

1 finding from 1 review

Er:YAG laser surface debridement before bone augmentation vs Plastic curettes plus saline solution before bone augmentation

Change in probing attachment level (PAL) · People with at least one dental implant affected by perimplantitis

Er:YAG laser surface debridement before bone augmentation showed no clear difference in change in probing attachment level (PAL gain) compared with plastic curettes plus saline solution before bone augmentation; GRADE not reported.

1 finding from 1 review

Subepithelial connective tissue graft (palate) at implant placement vs No augmentation

Marginal bone level change · Partially edentulous patients receiving posterior mandibular implants

Subepithelial connective tissue graft (palate) at implant placement showed no clear difference in peri-implant marginal bone level change compared with no augmentation; GRADE not reported.

1 finding from 1 review

Ceramic implant abutment vs Metal implant abutments (titanium)

Overall success rate · Patients receiving implant-supported single crowns / short-span FDPs
1 finding from 1 review
  • Andersson 2003: 94% (16/17) ceramic vs 100% (12/12) titanium; Andersson 2001: 93% (28/30) ceramic vs 100% (35/35) titanium; no statistical analysis provided; no measurable / non-significant differences in alveolar bone…
    2 studies · 107 participants
    GRADE not reported

Alternative alloy FDP (e.g., Ceramalloy II / base-metal / palladium-silver) vs High-gold content control alloy FDP (Olympia)

Restoration survival · Patients receiving crowns and FDPs; split-mouth, 10-year

Alternative alloy FDP (e.g., Ceramalloy II / base-metal /… led to higher restoration survival (Ceramalloy II versus Olympia) compared with high-gold content control alloy FDP (Olympia); GRADE not reported.

1 finding from 1 review

Er:YAG laser debridement vs Manual debridement plus chlorhexidine irrigation/gel

Change in gingival recession (REC) · People with at least one dental implant affected by perimplantitis

Er:YAG laser debridement showed no clear difference in change in gingival recession (REC) compared with manual debridement plus chlorhexidine irrigation/gel; GRADE not reported.

1 finding from 1 review

Denzir all-ceramic FDP vs In-Ceram Zirconia all-ceramic FDP

Reconstruction failure / chip fractures (12 months) · Patients with all-ceramic implant FDP reconstructions; parallel group, 12-month
1 finding from 1 review