Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

iMRI image‐guided surgery vs surgery

Overall survival · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

iMRI image‐guided surgery vs surgery

Progression‐free survival · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

iMRI image‐guided surgery vs surgery

Quality of life · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

5‐ALA image‐guided surgery vs surgery

Adverse events · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

5‐ALA image‐guided surgery vs surgery

Overall survival · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

5‐ALA image‐guided surgery vs surgery

Progression‐free survival · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

5‐ALA image‐guided surgery vs surgery

Quality of life · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

Surgery vs any Medical Therapy

NON ‐ Healing (persistence or recurrence) · people with anal fissures

Any Surgery leads to lower NON ‐ Healing (persistence or recurrence) compared with any Medical Therapy (high certainty).

1 finding from 1 review

Prehabilitation vs no prehabilitation

Functional capacity · Patients with outcomes after colorectal cancer surgery
3 findings from 1 review

Vitrectomy vs vitreous tap biopsy and antibiotic injection

Additional surgical procedure, including vitrectomy and cataract surgery. · people with endophthalmitis following intraocular surgery

Vitrectomy showed no clear difference in additional surgical procedure, including vitrectomy and cataract… compared with vitreous tap biopsy and antibiotic injection (low certainty).

1 finding from 1 review

Topical mydriatics vs intracameral mydriatics

AE: cystoid macular edema · patients undergoing cataract surgery

Topical mydriatics showed no clear difference in AE: cystoid macular edema compared with intracameral mydriatics (low certainty).

2 findings from 1 review