The review found no eligible studies for this question.
Vaginal misoprostol may leads to higher complete miscarriage compared with placebo (low certainty).
The review found no eligible studies for this question.
Vaginal misoprostol showed no clear difference in nausea compared with placebo (low certainty).
Vaginal misoprostol showed no clear difference in diarrhoea compared with placebo (low certainty).
It is very uncertain whether vaginal misoprostol changes blood loss: haemoglobin difference > 10 g/L compared with placebo (very low certainty).
It is very uncertain whether vaginal misoprostol changes pain (opiate use) compared with placebo (very low certainty).
Vaginal misoprostol showed no clear difference in woman’s satisfaction/acceptability of method compared with placebo (low certainty).
Progestogen showed no clear difference in miscarriage (all trials) compared with placebo/no treatment (moderate certainty).
Progestogen showed no clear difference in live birth rate compared with placebo/no treatment (moderate certainty).
It is very uncertain whether progestogen changes preterm birth compared with placebo/no treatment (very low certainty).
Vitamin D supplementation probably leads to lower pre‐eclampsia compared with placebo or no intervention (moderate certainty).
The review found no eligible studies for this question.
Vitamin D + calcium supplementation may leads to higher preterm birth (less than 37 weeks' gestation) compared with placebo or no intervention (low certainty).
It is very uncertain whether vitamin D + calcium supplementation changes low birthweight (less than 2500 g) compared with placebo or no intervention (very low certainty).
Vitamin D supplementation probably leads to lower gestational diabetes compared with placebo or no intervention (moderate certainty).
Vitamin D supplementation may leads to lower maternal adverse events: severe postpartum haemorrhage compared with placebo or no intervention (low certainty).
It is very uncertain whether vitamin D supplementation changes maternal adverse event: nephritic syndrome compared with placebo or no intervention (very low certainty).
Vitamin D supplementation showed no clear difference in preterm birth (less than 37 weeks' gestation) compared with placebo or no intervention (low certainty).