Corticosteroids (dexamethasone) may leads to higher number of participants with normal physical joint function ‐ normal… compared with placebo (low certainty).
Corticosteroids (dexamethasone) showed no clear difference in number of days of antibiotic treatment ‐ number of days of… compared with placebo (low certainty).
Maternal outcomes: corticosteroids showed no clear difference in maternal death compared with placebo or no treatment (moderate certainty).
Maternal outcomes: corticosteroids showed no clear difference in chorioamnionitis№ of participants: 8374(15 RCTs) compared with placebo or no treatment (moderate certainty).
Maternal outcomes: corticosteroids showed no clear difference in endometritis№ of participants: 6764(10 RCTs) compared with placebo or no treatment (moderate certainty).
Increased showed no clear difference in treatment failure: need for systemic corticosteroids (ITT) compared with stable doses of inhaled corticosteroids (moderate certainty).
It is very uncertain whether increased changes treatment failure: need for systemic corticosteroids (of those… compared with stable doses of inhaled corticosteroids (very low certainty).
Early systemic postnatal corticosteroids showed no clear difference in mortality at latest reported age compared with placebo or no treatment (high certainty).
Early systemic postnatal corticosteroids probably leads to lower BPD (36 weeks' PMA) compared with placebo or no treatment (moderate certainty).
Early systemic postnatal corticosteroids leads to lower mortality or BPD at 36 weeks' PMA compared with placebo or no treatment (high certainty).
Early systemic postnatal corticosteroids leads to higher gastrointestinal perforation during primary hospitalisation compared with placebo or no treatment (high certainty).
Early systemic postnatal corticosteroids leads to higher cerebral palsy at latest reported age compared with placebo or no treatment (high certainty).
Early systemic postnatal corticosteroids showed no clear difference in mortality or cerebral palsy at latest reported age compared with placebo or no treatment (high certainty).
Inhaled corticosteroids plus standard care showed no clear difference in all‐cause mortality compared with standard care (with or without placebo) (low certainty).
Inhaled corticosteroids plus standard care probably leads to lower admission to hospital or death compared with standard care (with or without placebo) (moderate certainty).
Inhaled corticosteroids plus standard care probably leads to higher symptom resolution: all initial symptoms resolved at day 14 compared with standard care (with or without placebo) (moderate certainty).
Inhaled corticosteroids plus standard care showed no clear difference in symptom resolution: duration to symptoms resolved compared with standard care (with or without placebo) (low certainty).