Findings

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Evidence found and GRADE certainty

4,534 questions · 5,247 findings · 456 reviews

No studies found 1,142 · 21.8%GRADE not reported 1,503 · 28.6%Very low 1,040 · 19.8%Low 869 · 16.6%Moderate 554 · 10.6%High 139 · 2.6%

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Extraction of lower deciduous canines vs No active treatment (control)

Amount of crowding · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether extraction of lower deciduous canines changes amount of crowding (lower incisor crowding, change) at 1-2 years compared with no active treatment (control) (very low certainty).

1 finding from 1 review

Cervical pull headgear vs Minor interceptive procedures (control)

Lower incisors to mandible (relationship of lower front teeth to the mandible) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Cervical pull headgear showed no clear difference in lower incisors to mandible at 2 years compared with minor interceptive procedures (control); GRADE not reported.

1 finding from 1 review

Clinical examination with risk-based recall vs Clinical examination with 24-month recall

Periodontal disease: gingival bleeding (percentage of sites) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in periodontal disease: gingival bleeding (percentage of sites) compared with clinical examination with 24-month recall (high certainty).

1 finding from 1 review

Clinical examination with risk-based recall vs Clinical examination with 6-month recall

Periodontal disease: gingival bleeding (percentage of sites) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in periodontal disease: gingival bleeding (percentage of sites) compared with clinical examination with 6-month recall (high certainty).

1 finding from 1 review

Clinical examination with 24-month recall vs Clinical examination with 6-month recall

Periodontal disease: gingival bleeding (percentage of sites) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with 24-month recall showed no clear difference in periodontal disease: gingival bleeding (percentage of sites) compared with clinical examination with 6-month recall (moderate certainty).

1 finding from 1 review

Intervention not reported

Transepidermal water loss (TEWL) Measured using temperature‐adjusted g/m²/h with the Tewameter TM 300 (Courage + Khazaka, Cologne, Germany) Hahnel 2017: measured at 56 ± 4 days Shishido 2017: measured 15 minutes after wiping the skin with a dry to... · people 60 years of age and older
1 finding from 1 review

Hypofractionated radiotherapy vs daily conventionally fractionated radiotherapy

Overall survival for subgroup age 60 years and older glioblastoma · high‐grade glioma

Hypofractionated radiotherapy showed no clear difference in overall survival for subgroup aged ≥ 60 years glioblastoma compared with daily conventionally fractionated radiotherapy (high certainty).

1 finding from 1 review

Combined dietary and physical activity interventions with a caregiver component vs interventions without a caregiver component

Children's percentage of total energy intake from saturated fat Measured by food frequency questionnaire and 24‐hour recall · children aged 4 to 14 years
1 finding from 1 review

Physical activity interventions with a caregiver component vs interventions without a caregiver component

Children's percentage of total energy intake from saturated fat Measured by food frequency questionnaire and 24‐hour recall · children aged 3 to 11 years

The review found no eligible studies for this question.

1 finding from 1 review

Digital targeted client communication via mobile devices vs standard care or no intervention (parents of children aged under five years)

Service utilisation – attendance for necessary healthcare (attendance for vaccinations at 6–12 months, attendance at HIV medical appointments) · parents of children aged < 5 years

Digital targeted client communication via mobile devices may leads to higher service utilisation – attendance for necessary healthcare… compared with standard care or no intervention (parents of children aged under… (low certainty).

1 finding from 1 review