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Evidence found and GRADE certainty

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

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No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Traditional antenatal CTG vs no antenatal CTG (women at increased risk of complication)

Apgar score less than 7 at 5 minutes · Pregnant women with/without complications

It is very uncertain whether traditional antenatal CTG changes apgar less than 7 at 5 minutes compared with no antenatal CTG (women at increased risk of complication) (very low certainty).

1 finding from 1 review

Traditional antenatal CTG vs no antenatal CTG (women at increased risk of complication)

Admission to neonatal special care unit or intensive care unit · Pregnant women with/without complications

Traditional antenatal CTG showed no clear difference in admission to neonatal special care unit or intensive care unit compared with no antenatal CTG (women at increased risk of complication) (low certainty).

1 finding from 1 review

Computerised antenatal CTG vs traditional antenatal CTG (women at increased risk of complications)

Perinatal mortality · Pregnant women with/without complications

Computerised antenatal CTG probably leads to lower perinatal mortality compared with traditional antenatal CTG (women at increased risk of complications) (moderate certainty).

1 finding from 1 review

Tranexamic acid vs placebo/no treatment

Blood loss > 400 mL or > 500 mL · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage

Tranexamic acid probably leads to lower blood loss > 400 mL or > 500 mL compared with placebo/no treatment (moderate certainty).

1 finding from 1 review

Tranexamic acid vs placebo/no treatment

Blood loss > 1000 mL · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage

Tranexamic acid probably leads to lower blood loss > 1000 mL compared with placebo/no treatment (moderate certainty).

1 finding from 1 review

Tranexamic acid vs placebo/no treatment

Use of additional medical interventions to control PPH · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage

Tranexamic acid probably leads to lower use of additional medical interventions to control PPH compared with placebo/no treatment (moderate certainty).

1 finding from 1 review

Tranexamic acid vs placebo/no treatment

Thromboembolic events · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage

Tranexamic acid showed no clear difference in thromboembolic events compared with placebo/no treatment (low certainty).

1 finding from 1 review