Overall mortality at 28 days · critically ill participants with ALI and ARDS
INO showed no clear difference in overall mortality at 28 days compared with control group (moderate certainty).
1 finding from 1 review
Respiratory effects: PaO2/FiO2 ratio up to 24 hours after initiation of therapy · critically ill participants with ALI and ARDS
INO probably leads to higher paO2/FiO2 up to 24 hours compared with control group (moderate certainty).
1 finding from 1 review
Oxygenation index (absolute values) after 24 hours of treatment · critically ill participants with ALI and ARDS
INO showed no clear difference in oxygenation index, 24 hours compared with control group (moderate certainty).
1 finding from 1 review
Ventilator‐free days up to day 28 · critically ill participants with ALI and ARDS
INO showed no clear difference in ventilation‐free days, up to 30 days compared with control group (high certainty).
1 finding from 1 review
Incidence of renal impairment · critically ill participants with ALI and ARDS
INO leads to higher renal impairment compared with control group (high certainty).
1 finding from 1 review
Weight (kg) · preterm infants after hospital discharge
2 findings from 1 review
Crown‐heel length (mm) · preterm infants after hospital discharge
2 findings from 1 review
Head circumference (mm) · preterm infants after hospital discharge
2 findings from 1 review
Mental development index (MDI) at 18 months · preterm infants after hospital discharge
1 finding from 1 review
Crown‐heel length (mm) · preterm infants after hospital discharge
2 findings from 1 review
Head circumference (mm) · preterm infants after hospital discharge
2 findings from 1 review
Mental development index (MDI) at 18 months · preterm infants after hospital discharge
1 finding from 1 review
Weight (kg) · preterm infants after hospital discharge
2 findings from 1 review
Intervention not reported
Number of participants with improved complete spontaneous bowel movement (CSBM) of greater than three times per week at two‐month · children with chronic constipation
It is very uncertain whether the intervention changes number of participants with improved complete spontaneous bowel… (very low certainty).
1 finding from 1 review
Intervention not reported
Number of participants with improved colonic transit · children with chronic constipation
It is very uncertain whether the intervention changes number of participants with improved colonic transit (very low certainty).
1 finding from 1 review
Intervention not reported
Number of participants with improved symptoms related to soiling · children with chronic constipation
It is very uncertain whether the intervention changes number of participants with improved symptoms related to soiling (very low certainty).
1 finding from 1 review
Intervention not reported
Number of participants with improved quality of life · children with chronic constipation
It is very uncertain whether the intervention changes number of participants with improved quality of life (very low certainty).
1 finding from 1 review
Intervention not reported
Social interaction and communication ‐ Parental ATEC score (scale from 0 to 40) · children with ASD
1 finding from 1 review
Intervention not reported
Social interaction and communication ‐ Clinician ATEC score (scale from 0 to 40) · children with ASD
1 finding from 1 review
Intervention not reported
Behavioral problems ‐ Parental ATEC score · children with ASD
1 finding from 1 review