Findings

What do systematic reviews say?

3,696 questions · 3,815 findings · 855 reviews

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No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Costs (fixation materials, hospital bed days, retreatment) · Adults over 18 years of age with fractures of the facial skeleton including the mandible, maxilla, zygoma (malar); studies on fractures of…

The review found no eligible studies for this question.

1 finding from 1 review

Resorbable versus titanium plates for facial fractures 2009 · Cochrane All outcomes
Up to 3 years postoperatively
Planned cost outcome not assessed: none of the retrieved studies met the inclusion criteria, so no data were available for analysis. Verbatim (Effects of interventions): "Although 53 studies were retrieved in our…
0 studies
No studies found

Intervention not reported

Psychological morbidity (immediately ‐ day 28 post‐donation) · Haemopoietic stem cell donors

1 finding from 1 review

Bone marrow harvest versus peripheral stem cell collection for haemopoietic stem cell donation in healthy donors 2009 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 214 participants
Low

Intervention not reported

All‐cause mortality at 2 days ‐ immediate treatment · patients with acute myocardial infarction1

The intervention leads to lower all‐cause mortality at 2 days ‐ immediate treatment (high certainty).

1 finding from 1 review

Effect of early treatment with anti‐hypertensive drugs on short and long‐term mortality in patients with an acute… 2009 · Cochrane Headline outcomes only
RR 0.81 [0.74, 0.89]
6 studies · 82624 participants
High

Intervention not reported

All‐cause mortality at 10 days‐ short‐term treatment · patients with acute myocardial infarction1

The intervention leads to lower all‐cause mortality at 10 days‐ short‐term treatment (high certainty).

1 finding from 1 review

Effect of early treatment with anti‐hypertensive drugs on short and long‐term mortality in patients with an acute… 2009 · Cochrane Headline outcomes only
RR 0.91 [0.86, 0.97]
6 studies · 78178 participants
High

Intervention not reported

All‐cause mortality at 2 days ‐ immediate treatment · acute myocardial infarction1

The intervention showed no clear difference in all‐cause mortality at 2 days ‐ immediate treatment (high certainty).

1 finding from 1 review

Effect of early treatment with anti‐hypertensive drugs on short and long‐term mortality in patients with an acute… 2009 · Cochrane Headline outcomes only
RR 0.91 [0.82, 1]
3 studies · 77414 participants
High

Intervention not reported

All‐cause mortality at 10 days ‐ short‐term treatment · acute myocardial infarction1

The intervention leads to lower all‐cause mortality at 10 days ‐ short‐term treatment (high certainty).

1 finding from 1 review

Effect of early treatment with anti‐hypertensive drugs on short and long‐term mortality in patients with an acute… 2009 · Cochrane Headline outcomes only
RR 0.93 [0.87, 0.98]
10 studies · 84311 participants
High

Intervention not reported

All‐cause mortality at 2 days ‐ immediate treatment · patients with acute myocardial infarction1

The intervention showed no clear difference in all‐cause mortality at 2 days ‐ immediate treatment (low certainty).

1 finding from 1 review

Effect of early treatment with anti‐hypertensive drugs on short and long‐term mortality in patients with an acute… 2009 · Cochrane Headline outcomes only
RR 0.95 [0.85, 1.07]
6 studies · 68007 participants
Low

Intervention not reported

All‐cause mortality at 10 days ‐ short‐term treatment · patients with acute myocardial infarction1

The intervention showed no clear difference in all‐cause mortality at 10 days ‐ short‐term treatment (high certainty).

1 finding from 1 review

Effect of early treatment with anti‐hypertensive drugs on short and long‐term mortality in patients with an acute… 2009 · Cochrane Headline outcomes only
RR 0.96 [0.91, 1.02]
14 studies · 71457 participants
High

Intervention not reported

All‐cause mortality at 2 days ‐ immediate treatment · patients with acute myocardial infarction or stroke1

It is very uncertain whether the intervention changes all‐cause mortality at 2 days ‐ immediate treatment (very low certainty).

1 finding from 1 review

Effect of early treatment with anti‐hypertensive drugs on short and long‐term mortality in patients with an acute… 2009 · Cochrane Headline outcomes only
RR 2.33 [0.62, 8.78]
3 studies · 242 participants
Very low

Intervention not reported

All‐cause mortality at 10 days ‐ short‐term treatment · patients with acute myocardial infarction or stroke1

It is very uncertain whether the intervention changes all‐cause mortality at 10 days ‐ short‐term treatment (very low certainty).

1 finding from 1 review

Effect of early treatment with anti‐hypertensive drugs on short and long‐term mortality in patients with an acute… 2009 · Cochrane Headline outcomes only
RR 1.01 [0.73, 1.38]
15 studies · 1900 participants
Very low

Monetary incentives: addition of monetary reward vs no monetary reward

Target behaviour: average number of dolls assembled per day · patients with schizophrenia1

1 finding from 1 review

Monetary incentives for schizophrenia 2009 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Very low

Systemic oral acyclovir vs placebo or no treatment

Duration and time of healing of intraoral (oral) lesions; number of individuals with oral lesions · Children and young adults under 25 years with primary herpetic gingivostomatitis (with or without herpes labialis)

Systemic oral acyclovir led to lower number of individuals with oral lesions (8 days after… compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Acyclovir for treating primary herpetic gingivostomatitis 2008 · Cochrane All outcomes
8 days after administration
RR 0.10 [0.02, 0.38]
1 study · 72 participants
GRADE not reported

Systemic oral acyclovir vs placebo or no treatment

Direct costs (medication, hospital bed days) · Children and young adults under 25 years with primary herpetic gingivostomatitis (with or without herpes labialis)

The review found no eligible studies for this question.

1 finding from 1 review

Acyclovir for treating primary herpetic gingivostomatitis 2008 · Cochrane All outcomes
No data available in either included study.
Studies not reported
No studies found

Systemic oral acyclovir vs placebo or no treatment

Number of individuals with eating difficulties (8 days after administration); duration of eating difficulties · Children and young adults under 25 years with primary herpetic gingivostomatitis (with or without herpes labialis)

Systemic oral acyclovir led to lower number of individuals with eating difficulties (8 days after… compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Acyclovir for treating primary herpetic gingivostomatitis 2008 · Cochrane All outcomes
8 days after administration
RR 0.14 [0.03, 0.58]
1 study · 72 participants
GRADE not reported

Systemic oral acyclovir vs placebo or no treatment

Difficulty in drinking (number with drinking difficulties) · Children and young adults under 25 years with primary herpetic gingivostomatitis (with or without herpes labialis)

Systemic oral acyclovir led to lower number of individuals with drinking difficulties (8 days after… compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Acyclovir for treating primary herpetic gingivostomatitis 2008 · Cochrane All outcomes
8 days after administration
RR 0.11 [0.01, 0.83]
1 study · 72 participants
GRADE not reported

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole, itraconazole) vs placebo or no treatment

Length of hospital stay · Patients with cancer receiving chemotherapy and/or radiotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes
No trial reported this planned secondary outcome for any comparison in this review
Studies not reported
No studies found

Intervention not reported

Duration of diarrhea in days · children with measles

1 finding from 1 review

Vitamin A for treating measles in children 2005 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 249 participants
Moderate

Intervention not reported

Hospital stay in days · children with measles

1 finding from 1 review

Vitamin A for treating measles in children 2005 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 278 participants
Moderate

Intervention not reported

Duration of fever in days · children with measles

1 finding from 1 review

Vitamin A for treating measles in children 2005 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 149 participants
Moderate

PE vs intravenous immunoglobulin (IVIG)

Change in score (MMS) day 0 to day 15

1 finding from 1 review

Plasma exchange for generalised myasthenia gravis 2002 · Cochrane Headline outcomes only
no estimate extracted
1 study · 87 participants
High