Live birth rate per woman · women with polycystic ovary syndrome
Metformin combined with clomiphene citrate showed no clear difference in live birth rate per woman compared with clomiphene citrate alone (low certainty).
Gastrointestinal adverse events · women with polycystic ovary syndrome
Metformin combined with clomiphene citrate probably leads to higher adverse events (gastrointestinal) per woman compared with clomiphene citrate alone (moderate certainty).
Clinical pregnancy rate · women with polycystic ovary syndrome
Metformin combined with clomiphene citrate probably leads to higher clinical pregnancy rate per woman compared with clomiphene citrate alone (moderate certainty).
Number of participantswith at least one recurrent adenoma · people with a history of colorectal adenomas
Dietary fibre (all study interventions) showed no clear difference in number of participantswith at least one recurrent adenoma compared with control (low certainty).
1 finding from 1 review
Number of participantswith more than one adenoma · people with a history of colorectal adenomas
Dietary fibre (all study interventions) showed no clear difference in number of participantswith more than one adenoma compared with control (low certainty).
1 finding from 1 review
Number of participantswith at least one adenoma 1 cm or greater · people with a history of colorectal adenomas
Dietary fibre (all study interventions) showed no clear difference in number of participantswith at least one adenoma 1 cm or greater compared with control (low certainty).
1 finding from 1 review
Number of participantsdiagnosed with colorectal cancer · people with a history of colorectal adenomas
Dietary fibre (all study interventions) may leads to higher number of participantsdiagnosed with colorectal cancer compared with control (low certainty).
1 finding from 1 review
Intervention not reported
Survival at 1 year Estimated survival at 1 year based on trials of 6 and 9 months' duration · people with ALS/MND
1 finding from 1 review
Intervention not reported
Rate of decline in MVIC Expressed as arm megascore1 · people with ALS/MND
1 finding from 1 review
Intervention not reported
Rate of decline of % predicted FVC · people with ALS/MND
1 finding from 1 review
Intervention not reported
Rate of decline (per month) of functional rating scale (over a period of 9 months) Measured by ALSFRS‐R · people with ALS/MND
1 finding from 1 review
Intervention not reported
Health‐related quality of life Short Form 12 Health Survey (SF‐12) · people with ALS/MND
1 finding from 1 review
Intervention not reported
Adverse events · people with ALS/MND
1 finding from 1 review
Intervention not reported
Anatomic success (i.e. patent lacrimal passage after a period of at least six months after operation) · People with nasolacrimal duct obstruction
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Subjective success (i.e. resolution of symptoms of watering following surgery) · People with nasolacrimal duct obstruction
1 finding from 1 review
no estimate extracted
5 participants
Low
Intervention not reported
Intraoperative bleeding · People with nasolacrimal duct obstruction
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Postoperative bleeding · People with nasolacrimal duct obstruction
It is very uncertain whether the intervention changes postoperative bleeding (very low certainty).
1 finding from 1 review
Intervention not reported
Wound infection/gaping · People with nasolacrimal duct obstruction
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Occurrence of CIN2+ in histology at 18 months · women with ASCUS or LSIL
The intervention probably leads to higher occurrence of CIN2+ in histology at 18 months (moderate certainty).
1 finding from 1 review
Intervention not reported
Occurrence of CIN2+ in histology at 24 months · women with ASCUS or LSIL
The intervention showed no clear difference in occurrence of CIN2+ in histology at 24 months (low certainty).
1 finding from 1 review