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Evidence found and GRADE certainty

3,018 questions · 3,100 findings · 369 reviews · Headline outcomes only

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No studies found 774 · 25%GRADE not reported 108 · 3.5%Very low 727 · 23.5%Low 840 · 27.1%Moderate 474 · 15.3%High 177 · 5.7%

Intervention not reported

Failure of sustained virological response Absence of clearance of HCV RNA from the blood 6 months after treatment · patients with chronic hepatitis C

The intervention showed no clear difference in failure of sustained virological response Absence of clearance of… (moderate certainty).

1 finding from 1 review

Intervention not reported

Quality of life Different QoL scales · patients with chronic hepatitis C
1 finding from 1 review

Intervention not reported

Failure of normalisation of ALT at end of treatment · patients with chronic hepatitis C

The intervention may leads to lower failure of normalisation of ALT at end of treatment (low certainty).

1 finding from 1 review

Intervention not reported

Failure of normalisation of ALT at end of · patients with chronic hepatitis C

The intervention showed no clear difference in failure of normalisation of ALT at end of (low certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality or liver‐related morbidity · patients with chronic hepatitis C.

It is very uncertain whether the intervention changes all‐cause mortality or liver‐related morbidity (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse events · patients with chronic hepatitis C.

It is very uncertain whether the intervention changes adverse events (very low certainty).

1 finding from 1 review

Intervention not reported

Failure of sustained virological response Absence of clearance of HCV RNA from the blood 6 months after treatment · patients with chronic hepatitis C.

The intervention may leads to higher failure of sustained virological response Absence of clearance of… (low certainty).

1 finding from 1 review

Intervention not reported

Failure of end of treatment virological response Absence of clearance of HCV RNA from the blood at end of treatment · patients with chronic hepatitis C.

The intervention may leads to higher failure of end of treatment virological response Absence of… (low certainty).

1 finding from 1 review

Intervention not reported

Failure of normalisation of ALT at end of treatment · patients with chronic hepatitis C.

It is very uncertain whether the intervention changes failure of normalisation of ALT at end of treatment (very low certainty).

1 finding from 1 review

Intervention not reported

Failure of normalisation of ALT at end of · patients with chronic hepatitis C.

It is very uncertain whether the intervention changes failure of normalisation of ALT at end of (very low certainty).

1 finding from 1 review