General life satisfaction Quality of Life Interview section, scale of 1 to 7 · people with both severe mental illness and substance misuse
1 finding from 1 review
Lost to treatment · people with both severe mental illness and substance misuse
It is very uncertain whether non‐integrated models of care ‐ Assertive community treatment… changes leaving the study early: Lost to treatment compared with standard care (very low certainty).
1 finding from 1 review
Adverse event: Death ‐ not measured · people with both severe mental illness and substance misuse
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Catatonia: clinically important change in catatonia symptoms (improved at least 50% on the VAS) · catatonia in people with schizophrenia or SMI
It is very uncertain whether lorazepam changes catatonia: clinically important change in catatonia symptoms… compared with oxazepam (very low certainty).
1 finding from 1 review
Duration of hospital stay (days) for 'rescue' therapy · catatonia in people with schizophrenia or SMI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Satisfaction with care: clinically important change in satisfaction by informal care‐givers · catatonia in people with schizophrenia or SMI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Satisfaction with care: clinically important change in satisfaction by recipients of care · catatonia in people with schizophrenia or SMI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Global state: clinically important change in global state · catatonia in people with schizophrenia or SMI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects: clinically important adverse effectsassessed by: number of participants with a delayed memory deficitStudy duration: 4 weeks · catatonia in people with schizophrenia or SMI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
General functioning: clinically important change in specific aspects of functioning, such as life skills ‒ as defined by each of the studies · catatonia in people with schizophrenia or SMI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mental state: clinically important change in general mental state ‐ worsening psychosis · schizophrenia or related disorders
Modafinil showed no clear difference in mental state: clinically important change in general mental state ‐… compared with placebo (low certainty).
1 finding from 1 review
Cognitive function: average endpoint score** · schizophrenia or related disorders
1 finding from 1 review
Adverse effect/event(s) ‐ serious adverse events · schizophrenia or related disorders
It is very uncertain whether modafinil changes adverse effect/event(s) ‐ serious adverse events compared with placebo (very low certainty).
1 finding from 1 review
Global state: clinically important change in global state · schizophrenia or related disorders
It is very uncertain whether modafinil changes global state: clinically important change in global state compared with placebo (very low certainty).
1 finding from 1 review
Leaving the study early · schizophrenia or related disorders
Modafinil showed no clear difference in leaving the study early ‐ for any reason compared with placebo (moderate certainty).
1 finding from 1 review
Quality of life: 1a. Average endpoint scores on various scales (MSQoL‐54, high = good) ‐ short term · schizophrenia or related disorders
1 finding from 1 review
Hospital admissions · schizophrenia or related disorders
It is very uncertain whether modafinil changes service use: hospital admission compared with placebo (very low certainty).
1 finding from 1 review
Hospital admissions · people with schizophrenia or other serious mental illness
It is very uncertain whether peer support plus standard care changes service use: hospital admission – medium term compared with standard care (very low certainty).
1 finding from 1 review
Relapse · people with schizophrenia or other serious mental illness
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Global state: clinically important change in global state · people with schizophrenia or other serious mental illness
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found