HIV infection · High‐risk individuals (including serodiscordant couples, men who have sex with men and sex workers)
TDF probably leads to lower HIV infection compared with placebo (moderate certainty).
1 finding from 1 review
Serious adverse events · High‐risk individuals (including serodiscordant couples, men who have sex with men and sex workers)
TDF showed no clear difference in serious adverse events compared with placebo (moderate certainty).
1 finding from 1 review
Intervention not reported
Death (all cause) · HIV infected adults who meet the WHO criteria for commencing antiretroviral treatment.
The intervention showed no clear difference in death (all cause) (low certainty).
1 finding from 1 review
Intervention not reported
Proportion of patients achieving and maintaining undetectable viral load, e.g. less than 400 copies/ml · HIV infected adults who meet the WHO criteria for commencing antiretroviral treatment.
The intervention may leads to higher proportion of patients achieving and maintaining undetectable viral… (low certainty).
1 finding from 1 review
Intervention not reported
Proportion of patients achieving and maintaining undetectable viral load, e.g. less than 50 copies/ml · HIV infected adults who meet the WHO criteria for commencing antiretroviral treatment.
The intervention may leads to higher proportion of patients achieving and maintaining undetectable viral… (low certainty).
1 finding from 1 review
Intervention not reported
CD4+ count · HIV infected adults who meet the WHO criteria for commencing antiretroviral treatment.
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adherence ‐ not measured · patients with Improving outcomes in youth living with HIV
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mortality ‐ not measured · patients with Improving outcomes in youth living with HIV
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life ‐ not measured · patients with Improving outcomes in youth living with HIV
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Viral load · patients with Improving outcomes in youth living with HIV
1 finding from 1 review
Retention in care Number attending last · patients with Improving outcomes in youth living with HIV
Motivational interviewing showed no clear difference in retention in care Number attending last compared with control (moderate certainty).
1 finding from 1 review
Drug abuse Self reported use of marijuana · patients with Improving outcomes in youth living with HIV
Motivational interviewing showed no clear difference in drug abuse Self reported use of marijuana compared with control (moderate certainty).
1 finding from 1 review
Alcohol abuse Self reported alcohol use · patients with Improving outcomes in youth living with HIV
Motivational interviewing showed no clear difference in alcohol abuse Self reported alcohol use compared with control (moderate certainty).
1 finding from 1 review
Birth weight (grammes) Standard balance beam to nearest 10g · Pregnant and lactating women with HIV
1 finding from 1 review
Intervention not reported
Preterm < 37 wks · Pregnant women with HIV infection
The intervention showed no clear difference in preterm < 37 wks (moderate certainty).
1 finding from 1 review
Intervention not reported
Perinatal death · Pregnant women with HIV infection
The intervention showed no clear difference in perinatal death (moderate certainty).
1 finding from 1 review
Intervention not reported
Birth weight (g) Standard balance beam to within 10g after birth · Pregnant women with HIV infection
1 finding from 1 review
Intervention not reported
Mean change in Log10viral load at 6 weeks postpartum PCR Roche Amplicor version 1.5kit · Pregnant women with HIV infection
1 finding from 1 review
Intervention not reported
Overall weight gain during pregnancy Calibrated balance beam scale to the nearest 100g · Pregnant women with HIV infection
1 finding from 1 review
Intervention not reported
Birth weight Standard mechanical scale to nearest 50g · Pregnant women with HIV infection
1 finding from 1 review