Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

303 questions · 322 findings · 45 reviews

No studies found 31 · 9.6%GRADE not reported 22 · 6.8%Very low 99 · 30.7%Low 95 · 29.5%Moderate 68 · 21.1%High 7 · 2.2%

Intervention not reported

Number of patients with at least 30% pain reduction · Patients with fibromyalgia

It is very uncertain whether the intervention changes number of patients with at least 30% pain reduction (very low certainty).

1 finding from 1 review

Intervention not reported

Number of patients with a clinically important global improvement · Patients with fibromyalgia

It is very uncertain whether the intervention changes number of patients with a clinically important global improvement (very low certainty).

1 finding from 1 review

Intervention not reported

Discontinuation due to adverse events · Patients with fibromyalgia

It is very uncertain whether the intervention changes discontinuation due to adverse events (very low certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events · Patients with fibromyalgia

It is very uncertain whether the intervention changes serious adverse events (very low certainty).

1 finding from 1 review

Intervention not reported

Low dose SSRI versus placebo Luteal or continuous administration · women with premenstrual syndrome

The intervention probably leads to higher low dose SSRI versus placebo Luteal or continuous administration (moderate certainty).

1 finding from 1 review

Intervention not reported

Mod dose SSRI versus placebo Luteal or continuous administration · women with premenstrual syndrome

The intervention probably leads to higher mod dose SSRI versus placebo Luteal or continuous administration (moderate certainty).

1 finding from 1 review

Intervention not reported

High dose SSRIs versus placebo Continuous administration · women with premenstrual syndrome

The intervention probably leads to higher high dose SSRIs versus placebo Continuous administration (moderate certainty).

1 finding from 1 review