Development of type 2 diabetes · people at increased risk for developing type 2 diabetes
It is very uncertain whether summary of findings table for metformin plus intensive diet and… changes incidence of type 2 diabetes mellitus (N) Diagnostic criteria: 2… compared with intensive diet and exercise (very low certainty).
1 finding from 1 review
Serious adverse events · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cardiovascular mortality · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Non‐fatal myocardial infarction/stroke · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Socioeconomic effects Description: direct medical costs per participant · people at increased risk for developing type 2 diabetes
1 finding from 1 review
CVD events ‐ not reported · people at high risk of CVD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Total cholesterol (mmol/L), change from baseline · people at high risk of CVD
1 finding from 1 review
LDL cholesterol (mmol/L), change from baseline · people at high risk of CVD
1 finding from 1 review
HDL cholesterol (mmol/L), change from baseline · people at high risk of CVD
1 finding from 1 review
Triglycerides (mmol/L), change from baseline · people at high risk of CVD
1 finding from 1 review
Systolic blood pressure (mmHg), change from baseline · people at high risk of CVD
1 finding from 1 review
Diastolic blood pressure (mmHg), change from baseline · people at high risk of CVD
1 finding from 1 review
All‐cause mortality · people at increased risk for developing type 2 diabetes
It is very uncertain whether diet plus physical activity changes all‐cause mortality compared with standard treatment (very low certainty).
1 finding from 1 review
Development of type 2 diabetes · people at increased risk for developing type 2 diabetes
Diet plus physical activity probably leads to lower incidence of type 2 diabetes mellitus Diagnostic criteria: 3 trials… compared with standard treatment (moderate certainty).
1 finding from 1 review
SAEs · people at increased risk for developing type 2 diabetes
1 finding from 1 review
Cardiovascular mortality · people at increased risk for developing type 2 diabetes
It is very uncertain whether diet plus physical activity changes cardiovascular mortality compared with standard treatment (very low certainty).
1 finding from 1 review
Non‐fatal myocardial infarction/stroke · people at increased risk for developing type 2 diabetes
1 finding from 1 review
Health-related quality of life (after at least 5 years follow-up) · people at increased risk for developing type 2 diabetes
1 finding from 1 review
Costs (direct costs of interventions) · people at increased risk for developing type 2 diabetes
1 finding from 1 review