Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,100 questions · 1,164 findings · 107 reviews

No studies found 280 · 24.1%GRADE not reported 159 · 13.7%Very low 292 · 25.1%Low 274 · 23.5%Moderate 113 · 9.7%High 46 · 4%

Summary of findings table for metformin plus intensive diet and exercise vs intensive diet and exercise

Development of type 2 diabetes · people at increased risk for developing type 2 diabetes

It is very uncertain whether summary of findings table for metformin plus intensive diet and… changes incidence of type 2 diabetes mellitus (N) Diagnostic criteria: 2… compared with intensive diet and exercise (very low certainty).

1 finding from 1 review

Unfavourable oral hygiene and dietary habits (frequent sweet/sugar consumption; low toothbrushing frequency in early childhood) vs Favourable oral hygiene and dietary habits

Caries development in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)

Early-childhood oral hygiene and dietary habits show inconsistent associations with permanent-teeth caries, often losing significance after adjustment for past caries (2 studies; not pooled; not GRADE-rated).

1 finding from 1 review