Findings

What do systematic reviews say?

292 questions · 331 findings · 39 reviews

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No studies found 48 · 14.5%GRADE not reported 150 · 45.3%Very low 81 · 24.5%Low 24 · 7.3%Moderate 19 · 5.7%High 9 · 2.7%

Intervention not reported

Neonatal mortality · Term or late preterm newborns born in hospitals

The intervention showed no clear difference in neonatal mortality (low certainty).

1 finding from 1 review

Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
RR 0.11 [0.01, 2.04]
1 study · 140 participants
Low

Intervention not reported

Infections · Term or late preterm newborns born in hospitals

The intervention showed no clear difference in infections (high certainty).

1 finding from 1 review

Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
RR 0.98 [0.82, 1.16]
2 studies · 13033 participants
High

Intervention not reported

Neonatal mortality · Term or late preterm newborns born at home

The intervention showed no clear difference in neonatal mortality (low certainty).

1 finding from 1 review

Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
RR 0.2 [0.01, 4.03]
1 study · 202 participants
Low

Intervention not reported

Infections · Term or late preterm newborns born at home

The intervention probably leads to lower infections (moderate certainty).

1 finding from 1 review

Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
RR 0.69 [0.49, 0.95]
1 study · 203 participants
Moderate

Intervention not reported

Omphalitis (infections) · Term or late preterm newborns born in hospitals

The intervention probably leads to lower omphalitis (infections) (moderate certainty).

1 finding from 1 review

Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
RR 0.48 [0.28, 0.84]
2 studies · 809 participants
Moderate

Intervention not reported

Neonatal mortality · Term or late preterm newborns born in hospitals

1 finding from 1 review

Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Omphalitis · Term or late preterm newborns born in hospitals

The intervention showed no clear difference in omphalitis (low certainty).

1 finding from 1 review

Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
RR 0.88 [0.56, 1.39]
2 studies · 642 participants
Low

Intervention not reported

Neonatal mortality · Term or late preterm newborns born at home

The intervention leads to lower neonatal mortality (high certainty).

1 finding from 1 review

Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
RR 0.81 [0.71, 0.92]
3 studies · 31084 participants
High

Intervention not reported

Omphalitis · Term or late preterm newborns born at home

The intervention leads to lower omphalitis (high certainty).

1 finding from 1 review

Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
RR 0.48 [0.4, 0.57]
3 studies · 39925 participants
High

Intervention not reported

Neonatal mortality · Term or late preterm newborns born at home

The intervention showed no clear difference in neonatal mortality (high certainty).

1 finding from 1 review

Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
RR 1.03 [0.87, 1.23]
1 study · 17530 participants
High

Intervention not reported

Omphalitis · Term or late preterm newborns born at home

1 finding from 1 review

Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Neonatal mortality · Term or late preterm newborns born in hospitals

The intervention showed no clear difference in neonatal mortality (moderate certainty).

1 finding from 1 review

Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
RR 0.98 [0.67, 1.42]
1 study · 4904 participants
Moderate