Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Pyridoxine vs control

Pre‐eclampsia · pregnant women, either during the prenatal period or during labour.

Pyridoxine (B6) showed no clear difference in pre‐eclampsia ‐ Antenatal oral pyridoxine versus control compared with control (low certainty).

2 findings from 1 review

Pyridoxine vs control

Dental decay (increase in decayed, missing or filled teeth) ‐ Antenatal pyridoxine lozenges versus control · pregnant women, either during the prenatal period or during labour.

Pyridoxine (B6) may leads to lower dental decay (increase in decayed, missing or filled teeth) ‐… compared with control (low certainty).

1 finding from 1 review

Regional analgesia (with tocolysis) vs no intervention of regional analgesia (with or without tocolysis)

Caesarean section · patients with breech presentation

It is very uncertain whether regional analgesia (with tocolysis) changes caesarean section (primary) compared with no intervention of regional analgesia (with or without tocolysis) (very low certainty).

1 finding from 1 review

Regional analgesia (with tocolysis) vs no intervention of regional analgesia (with or without tocolysis)

Fetal bradycardia (primary) · patients with breech presentation

Regional analgesia (with tocolysis) showed no clear difference in fetal bradycardia (primary) compared with no intervention of regional analgesia (with or without tocolysis) (low certainty).

1 finding from 1 review

Regional analgesia (with tocolysis) vs no intervention of regional analgesia (with or without tocolysis)

Failed external cephalic version · patients with breech presentation

Regional analgesia (with tocolysis) probably leads to lower failed external cephalic version compared with no intervention of regional analgesia (with or without tocolysis) (moderate certainty).

1 finding from 1 review

Beta stimulant vs placebo

Cephalic vaginal birth not achieved (CS + breech vaginal birth) (primary) · patients with breech presentation

Beta stimulant probably leads to lower cephalic vaginal birth not achieved (CS + breech vaginal birth)… compared with placebo (moderate certainty).

1 finding from 1 review

Regional analgesia (with tocolysis) vs no intervention of regional analgesia (with or without tocolysis)

Cephalic presentation at birth (primary) · patients with breech presentation

It is very uncertain whether regional analgesia (with tocolysis) changes cephalic presentation at birth (primary) compared with no intervention of regional analgesia (with or without tocolysis) (very low certainty).

1 finding from 1 review

Regional analgesia (with tocolysis) vs no intervention of regional analgesia (with or without tocolysis)

Cephalic vaginal birth not achieved (CS + breech vaginal birth) (primary) · patients with breech presentation

Regional analgesia (with tocolysis) may leads to lower cephalic vaginal birth not achieved (CS + breech vaginal birth)… compared with no intervention of regional analgesia (with or without tocolysis) (low certainty).

1 finding from 1 review