Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,372 questions · 3,874 findings · 666 reviews

No studies found 431 · 11.1%GRADE not reported 783 · 20.2%Very low 995 · 25.7%Low 909 · 23.5%Moderate 596 · 15.4%High 160 · 4.1%

Intestinal trefoil factor (ITF), lower dose (336 mg) vs Intestinal trefoil factor (ITF), higher dose (2688 mg)

Oral mucositis (any severity) · Adults receiving chemotherapy alone for colorectal cancer
1 finding from 1 review

Low‐dose opioid based general anaesthesia vs high‐dose opioid based general anaesthesia

Mortality ‐ Death at any time after surgery · adult cardiac surgical patients

Low‐dose opioid‐based GA showed no clear difference in mortality ‐ Death at any time after surgery compared with high‐dose opioid‐based GA (low certainty).

1 finding from 1 review

Low‐dose opioid based general anaesthesia vs high‐dose opioid based general anaesthesia

Postoperative complications ‐ Myocardial infarction · adult cardiac surgical patients

Low‐dose opioid‐based GA showed no clear difference in postoperative myocardial infarction compared with high‐dose opioid‐based GA (low certainty).

1 finding from 1 review