Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,345 questions · 4,525 findings · 483 reviews

No studies found 1,024 · 22.6%GRADE not reported 388 · 8.6%Very low 1,172 · 25.9%Low 1,227 · 27.1%Moderate 576 · 12.7%High 138 · 3%

Prophylactic plasma transfusion before surgery/invasive procedures vs alternative haemostatic agents

All‐cause mortality up to 30 days ‐ not reported · patients undergoing non‐cardiac surgery/invasive procedures

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic plasma transfusion before surgery/invasive procedures vs alternative haemostatic agents

Bleeding ‐ major/excessive · patients undergoing non‐cardiac surgery/invasive procedures

It is very uncertain whether prophylactic plasma transfusion before surgery/invasive procedures changes major bleeding within 24 hours № of participants: 21 (1 RCT) compared with alternative haemostatic agents (very low certainty).

1 finding from 1 review

Laparoscopic vs open surgery

Septic abdominal complications (presence or absence) Clinical definition · patients with perforated peptic ulcer disease

Laparoscopic surgery showed no clear difference in septic abdominal complications (presence or absence) Clinical… compared with open surgery (low certainty).

1 finding from 1 review

Laparoscopic vs open surgery

Pulmonary complications (0 to 30 days) · patients with perforated peptic ulcer disease

Laparoscopic surgery showed no clear difference in pulmonary complications (presence or absence) compared with open surgery (low certainty).

1 finding from 1 review

Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery

The proportion of pressure ulcers healed · people with venous leg ulcers

It is very uncertain whether subfascial endoscopic perforator vein surgery (SEPS) + saphenous… changes proportion of ulcers healed at 12 months compared with saphenous surgery (very low certainty).

1 finding from 1 review