Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

296 questions · 315 findings · 41 reviews · Neonatal

No studies found 70 · 22.2%GRADE not reported 6 · 1.9%Very low 76 · 24.1%Low 92 · 29.2%Moderate 57 · 18.1%High 14 · 4.4%

Barbiturate treatment vs placebo or no treatment

Death or major neurodevelopmental disability · infants with perinatal asphyxia

It is very uncertain whether barbiturate treatment changes death or major neurodevelopmental disability compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Barbiturate treatment vs placebo or no treatment

Major neurodevelopmental disability at childhood · infants with perinatal asphyxia

It is very uncertain whether barbiturate treatment changes major neurodevelopmental disability compared with placebo or no treatment (very low certainty).

1 finding from 1 review