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Evidence found and GRADE certainty

4,587 questions · 5,761 findings · 495 reviews

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No studies found 1,011 · 17.5%GRADE not reported 1,797 · 31.2%Very low 1,100 · 19.1%Low 1,052 · 18.3%Moderate 649 · 11.3%High 152 · 2.6%

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Powered toothbrushing (as part of comprehensive oral care) vs Manual toothbrushing

Duration of mechanical ventilation · Critically ill patients receiving mechanical ventilation in ICU

Powered toothbrushing (as part of comprehensive oral care) showed no clear difference in duration of mechanical ventilation compared with manual toothbrushing (standard oral care); GRADE not reported.

1 finding from 1 review

Oral hygiene training (toothbrushing routine) of people with ID vs No oral hygiene training of people with ID

Plaque · Children and adults with mild to profound ID; setting residential or school

It is very uncertain whether oral hygiene training (toothbrushing routine) of people with ID changes plaque (short term) compared with no oral hygiene training of people with ID (very low certainty).

1 finding from 1 review

Oral hygiene training (toothbrushing routine) of people with ID vs No oral hygiene training of people with ID

Behaviour, attitude and self-efficacy (toothbrushing behaviour) (medium and long term) · Children and adults with mild to profound ID; setting residential or school
1 finding from 1 review
  • Oral hygiene interventions for people with intellectual disabilities 2019 · Cochrane All outcomes
    Long term (>12 months)
    Behaviour, attitude and self-efficacy (steps achieved in a toothbrushing routine), 100 days to 19 months; 59 participants (4 NRS); Very Low. Results not in a format for meta-analysis: 3 NRS (56 participants) reported…
    4 studies · 59 participants
    Very low

Oral hygiene training (toothbrushing routine) of people with ID vs No oral hygiene training of people with ID

Gingivitis · Children and adults with mild to profound ID; setting residential or school

It is very uncertain whether oral hygiene training (toothbrushing routine) of people with ID changes gingival inflammation (short term) compared with no oral hygiene training of people with ID (very low certainty).

1 finding from 1 review

Individualised oral care plan based on a multidisciplinary assessment vs usual care

Plaque · Adults aged 22 to 57 years with mixed levels of ID; setting residential
1 finding from 1 review
  • Oral hygiene interventions for people with intellectual disabilities 2019 · Cochrane All outcomes
    Medium term (6 weeks to 12 months)
    Individualised oral care plan vs usual care. Subjective Oral Hygiene Rating scale 1-5 and Improvement Differential, mean 12 months; SOHR 2.97 (intervention) vs 3.10 (control); improvement differential 38% vs 5%; 79…
    1 study · 79 participants
    Very low

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs oral antibiotics

Surgical site infection · Patients undergoing elective colorectal surgery

It is very uncertain whether summary of findings table ‐ Combined mechanical and oral antibiotic… changes surgical site infections compared with oral antibiotics alone (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs oral antibiotics

Anastomotic leakage · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in anastomotic leakage compared with oral antibiotics alone (low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs oral antibiotics

All‐cause mortality · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in mortality compared with oral antibiotics alone (low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs oral antibiotics

Postoperative ileus · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in incidence of postoperative ileus compared with oral antibiotics alone (low certainty).

1 finding from 1 review

Light-based detection and/or oral spectroscopy (e.g. ViziLite, VELscope, Microlux DL, Identafi 3000) vs Surgical or punch biopsy with histological assessment

Specificity · Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous oral lesions
1 finding from 1 review

Light-based detection and/or oral spectroscopy (e.g. ViziLite, VELscope, Microlux DL, Identafi 3000) vs Surgical or punch biopsy with histological assessment

Sensitivity · Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous oral lesions
1 finding from 1 review

Oral midazolam vs chloral hydrate

Level of sedation on a sedation assessment scale · children requiring sedation before procedures that require motion control, including echocardiography, lumbar puncture, micturating…
1 finding from 1 review