Oral mucositis (moderate to severe) · Adults with solid cancers receiving fluorouracil (5FU) and leucovorin
It is very uncertain whether oral cryotherapy for 30 minutes changes oral mucositis (moderate to severe) compared with oral cryotherapy for 60 minutes (very low certainty).
1 finding from 1 review
Oral mucositis (moderate to severe) · Patients with osteosarcoma (bone cancer) receiving high-dose methotrexate, vincristine and leucovorin
It is very uncertain whether oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… changes oral mucositis (moderate to severe) compared with low-dose leucovorin rinse (very low certainty).
1 finding from 1 review
Oral mucositis (moderate to severe) · All patients with cancer who are receiving treatment
Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… showed no clear difference in oral mucositis (moderate to severe) compared with control (no treatment or standard/usual oral care, e.g. saline rinse) (low certainty).
3 findings from 1 review
RR 0.43 [0.17, 1.09]
5 studies · 270 participants
Low
RR 1.01 [0.85, 1.20]
1 study · 122 participants
Very low
RR 0.52 [0.41, 0.65]
5 studies · 444 participants
Moderate
Oral mucositis (moderate to severe) · Adults with solid cancers receiving fluorouracil (5FU) and leucovorin
It is very uncertain whether oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… changes oral mucositis (moderate to severe) compared with chlorhexidine rinse (very low certainty).
1 finding from 1 review
Adverse events Mild to moderate swelling · Patients with thumb (trapeziometacarpal joint) osteoarthritis
It is very uncertain whether trapeziectomy with interpositional arthroplasty (T and IA) changes adverse events Mild to moderate swelling compared with artelon joint resurfacing (very low certainty).
1 finding from 1 review
Cramp intensity (on 3‐point scale; 1 = mild; 2 = moderate; 3 = severe) · patients with muscle cramps
1 finding from 1 review
Cramp intensity (on 3‐point scale; 1 = mild; 2 = moderate; 3 = severe) · patients with muscle cramps
1 finding from 1 review
Cramp intensity (on 3‐point scale; 1 = mild; 2 = moderate; 3 = severe) · patients with muscle cramps
1 finding from 1 review
Intervention not reported
Co‐operation during induction ‐ Video 'fairytale' vs. no audiovisual aid (Passive) ICC = 0 (perfect vs. poor‐moderate compliance) · children
It is very uncertain whether the intervention changes co‐operation during induction ‐ Video 'fairytale' vs. no audiovisual… (very low certainty).
1 finding from 1 review
Intervention not reported
Moderate to severe pain at IUC insertion (dichotomous) · women with IUC being inserted
The intervention may leads to lower moderate to severe pain at IUC insertion (dichotomous) (low certainty).
1 finding from 1 review
OR 0.3 [0.16, 0.55]
179 participants
Low
Condition‐specific anxiety symptoms As assessed by LSAS5 (scale from: 0 to 144, better indicated by a lower score. 55 to 65 points = moderate social anxiety disorder (Liebowitz 1987)) · adults with anxiety disorders
DCS and cognitive and behavioural therapies showed no clear difference in condition‐specific anxiety symptoms As assessed by LSAS5 (scale… compared with placebo and cognitive and behavioural therapies (moderate certainty).
1 finding from 1 review
Anxiety · adults with anxiety disorders
DCS and cognitive and behavioural therapies showed no clear difference in co‐morbid anxiety symptoms As assessed by BAI9 (scale from: 0 to 63,… compared with placebo and cognitive and behavioural therapies (low certainty).
1 finding from 1 review
Intervention not reported
At least 30% reduction in pain or equivalent (moderate) · adults with fibromyalgia
1 finding from 1 review
Intervention not reported
Physical activity Average daily minutes of moderate to vigorous (24 months) · whole communities (adults, adolescents and children)
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery
Tramadol showed no clear difference in number of patients with moderate to severe pain (PACU) compared with pethidine (low certainty).
1 finding from 1 review
Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery
1 finding from 1 review
Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery
1 finding from 1 review
Physician's assessment of global response of improvement, clear or excellent ‐ 6 weeks · people with atopic dermatitis
It is very uncertain whether tacrolimus 0.03% changes physician's assessment of global response of improvement, clear or… compared with corticosteroids (very low certainty).
1 finding from 1 review