Overall survival · people with single or solitary brain metastasis
Surgery plus whole brain radiotherapy (WBRT) showed no clear difference in overall survival compared with stereotactic radiosurgery plus WBRT (low certainty).
1 finding from 1 review
Adverse events (moderate) · people with single or solitary brain metastasis
It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events (moderate) compared with stereotactic radiosurgery plus WBRT (very low certainty).
1 finding from 1 review
Progression‐free survival · people with single or solitary brain metastasis
Surgery plus whole brain radiotherapy (WBRT) showed no clear difference in progression‐free survival compared with stereotactic radiosurgery plus WBRT (low certainty).
1 finding from 1 review
Overall survival · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) showed no clear difference in overall survival compared with WBRT (moderate certainty).
1 finding from 1 review
Disease‐specific survival · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) showed no clear difference in disease‐specific survival compared with WBRT (moderate certainty).
1 finding from 1 review
Local tumor control · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) probably leads to lower local tumor control compared with WBRT (moderate certainty).
1 finding from 1 review
Functionally independent survival (KPS) · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) showed no clear difference in functionally independent survival (KPS) compared with WBRT (moderate certainty).
1 finding from 1 review
Steroid use · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) may leads to lower steroid use compared with WBRT (low certainty).
1 finding from 1 review
Groin recurrence · patients with Early Vulvar Cancer
Primary Groin Radiotherapy showed no clear difference in groin recurrence compared with primary Groin Surgery (low certainty).
1 finding from 1 review
Disease specific mortality · patients with Early Vulvar Cancer
Primary Groin Radiotherapy showed no clear difference in disease specific mortality compared with primary Groin Surgery (low certainty).
1 finding from 1 review
Intervention not reported
Intervention: radiotherapy Comparison: no adjuvant treatment Outcome: neurocognitive impairment at 5‐ to 6‐year · people with glioma surviving at least two years
It is very uncertain whether the intervention changes intervention: radiotherapy Comparison: no adjuvant treatment… (very low certainty).
1 finding from 1 review
Intervention not reported
Intervention: radiotherapy Comparison: no adjuvant treatment Outcome: neurocognitive impairment at 12 year · people with glioma surviving at least two years
It is very uncertain whether the intervention changes intervention: radiotherapy Comparison: no adjuvant treatment… (very low certainty).
1 finding from 1 review
Intervention not reported
Intervention: radiotherapy Comparison: no adjuvant treatment Outcome: neurocognitive impairment at 2 year · people with glioma surviving at least two years
It is very uncertain whether the intervention changes intervention: radiotherapy Comparison: no adjuvant treatment… (very low certainty).
1 finding from 1 review
Intervention not reported
Intervention: radiotherapy Comparison: chemotherapy Outcome: neurocognitive impairment at 3 year · people with glioma surviving at least two years
The intervention showed no clear difference in intervention: radiotherapy Comparison: chemotherapy Outcome:… (low certainty).
1 finding from 1 review
Intervention not reported
Intervention: high‐dose radiotherapy Comparison: low‐dose radiotherapy Outcome: neurocognitive impairment at 2 years after treatment · people with glioma surviving at least two years
It is very uncertain whether the intervention changes intervention: high‐dose radiotherapy Comparison: low‐dose… (very low certainty).
1 finding from 1 review
Intervention not reported
Intervention: high‐dose radiotherapy Comparison: low‐dose radiotherapy Outcome: neurocognitive impairment at 5 years after treatment · people with glioma surviving at least two years
It is very uncertain whether the intervention changes intervention: high‐dose radiotherapy Comparison: low‐dose… (very low certainty).
1 finding from 1 review
Intervention not reported
Intervention: chemoradiotherapy Comparison: radiotherapy Outcome: neurocognitive impairment at 3 years after treatment · people with glioma surviving at least two years
The intervention showed no clear difference in intervention: chemoradiotherapy Comparison: radiotherapy Outcome:… (low certainty).
1 finding from 1 review
Intervention not reported
Intervention: stereotactic conformal radiotherapy Comparison: radiotherapy Outcome: neurocognitive impairment at 5 years after treatment · people with glioma surviving at least two years
The intervention showed no clear difference in intervention: stereotactic conformal radiotherapy Comparison:… (low certainty).
1 finding from 1 review
All‐cause mortality · People undergoing radiation therapy for head and neck cancer
Hyperbaric oxygen leads to lower mortality compared with air breathing to enhance the effectiveness of radiotherapy (high certainty).
1 finding from 1 review
Failure of local tumour control ‐ not reported · People undergoing radiation therapy for head and neck cancer
Hyperbaric oxygen probably leads to lower failure of local tumour control (local control) compared with air breathing to enhance the effectiveness of radiotherapy (moderate certainty).
1 finding from 1 review